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. 2022 Oct 13:12:1020608.
doi: 10.3389/fcimb.2022.1020608. eCollection 2022.

Inseparable companions: Fungal viruses as regulators of fungal fitness and host adaptation

Vanda Lerer  1 , Neta Shlezinger  1
Affiliations

Inseparable companions: Fungal viruses as regulators of fungal fitness and host adaptation

Vanda Lerer et al. Front Cell Infect Microbiol. .
No abstract available

Keywords: RCD; fungal fitness; fungal virulence; host adaptation; host-pathogen interactions; multipartite interaction; mycovirus; symbiosis.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The “Russian doll” model of multipartite RCD-driven pathosystem: Mycovirus, fungal pathogen, animal/plant host. 1. Animal/plant host induction of regulated cell death (RCD) pathways in the fungus to eliminate fungal spread. 2. Mycoviral-mediated inhibition of RCD or activation of survival mechanisms in fungal cells to prevent fungal host cells from dying. 3.Mycoviral immunomodulation. Mycoviral proteins may serve as PAMPs sensed by animal/plant cell PRRs and directly stimulate or block multiple inflammatory and cell death signaling pathways.
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