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Case Reports
. 2022 Oct 14:9:1004554.
doi: 10.3389/fsurg.2022.1004554. eCollection 2022.

Conjunctival squamous cell carcinoma with massive apoptosis and immune cell infiltration: A case report

Gang Du  1 , Jun Qiao  2 , Xunwen Lei  1 , Ruiqin Han  3
Affiliations
Case Reports

Conjunctival squamous cell carcinoma with massive apoptosis and immune cell infiltration: A case report

Gang Du et al. Front Surg. .

Abstract

This case reports a rare case of conjunctival squamous cell carcinoma in China. The elderly (86-year-old) female patient was diagnosed and treated effectively after three times of diagnosis. During this period, she was misdiagnosed and ineffective treatment for many times. Therefore, we propose to make an integrated diagnosis based on histopathological diagnosis, combined with a variety of diagnostic methods including MRI and CDFI, supplemented by updated multiple immunohistochemically techniques, so as to achieve the purpose of accurate diagnosis.

Keywords: SCC; apoptosis; case—based content filtering algorithm; conjunctival squamous cell carcinoma; immune cell infiltration.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Ocular pathological features. (A) the patient’s left upper eyelid was red and swollen, the skin lines disappeared, and it was difficult to open his eyes. (B) the patient's upper eyelid can reach a size of about 30 mm × 20 mm mass with unclear boundary, hard quality and poor activity. (C) the patient had bulbar conjunctival congestion, edema and corneal conjunctivalization.
Figure 2
Figure 2
MRI examination and histopathological verification. (A) MRI examination of the patient's orbit. (B) enhanced MRI of the patient's orbit. (C,D), histopathological verification of tumor tissue in SCC patient.
Figure 3
Figure 3
Detection the cell apoptosis by mIHC.
Figure 4
Figure 4
Detection the immune cells infiltration by mIHC.
See this image and copyright information in PMC

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