Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Oct 16;10(29):10820-10822.
doi: 10.12998/wjcc.v10.i29.10820.

Effect of gender on the reliability of COVID-19 rapid antigen test among elderly

Affiliations

Effect of gender on the reliability of COVID-19 rapid antigen test among elderly

Wassan Nori et al. World J Clin Cases. .

Abstract

Defining con-founders that affect the reliability of diagnostic tests for coronavirus disease 2019 is vital to breaking the chain of infection. The elderly population is a higher risk group for the emerging virus. However, gender seems to exert a critical role in modifying the infection risk among women owing to hormonal changes. The menopause transition is an exceptional period for older women where the protective and immunomodulatory effects of the estrogen hormone are lost. Accordingly, attention should be given to postmenopausal women since they will have an increased risk compared to their pre-menopausal peers.

Keywords: Age; COVID-19; Gender; Postmenopausal women; Rapid antigen test; Real-time reverse transcription-polymerase chain reaction.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Similar articles

Cited by

References

    1. Tabain I, Cucevic D, Skreb N, Mrzljak A, Ferencak I, Hruskar Z, Misic A, Kuzle J, Skoda AM, Jankovic H, Vilibic-Cavlek T. Field evaluation of COVID-19 rapid antigen test: Are rapid antigen tests less reliable among the elderly? World J Clin Cases. 2022;10:6456–6463. - PMC - PubMed
    1. Tazerji SS, Shahabinejad F, Tokasi M, Rad MA, Khan MS, Safdar M, Filipiak KJ, Szarpak L, Dzieciatkowski T, Jurgiel J, Duarte PM, Rahman MT, Sobur MA, Islam MS, Ahmed A, Shaheen MNF, Shehata AA, Gharieb R, Fawzy M, Malik YS, Jaganathasamy N, Rajendran VO, Subbaram K, Ali PSS, Ali S, Rehman SU, Ozaslan M, Khan G, Saeed M, Younas U, Imran S, Junejo Y, Arabkarami P, Hogan U, Rodriguez-Morales AJ. Global data analysis and risk factors associated with morbidity and mortality of COVID-19. Gene Rep. 2022;26:101505. - PMC - PubMed
    1. Mukherjee S, Pahan K. Is COVID-19 Gender-sensitive? J Neuroimmune Pharmacol. 2021;16:38–47. - PMC - PubMed
    1. Ni W, Yang X, Yang D, Bao J, Li R, Xiao Y, Hou C, Wang H, Liu J, Xu Y, Cao Z, Gao Z. Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19. Crit Care. 2020;24:422. - PMC - PubMed
    1. Al-Lami RA, Urban RJ, Volpi E, Algburi AMA, Baillargeon J. Sex Hormones and Novel Corona Virus Infectious Disease (COVID-19) Mayo Clin Proc. 2020;95:1710–1714. - PMC - PubMed