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. 2022 Oct 28;101(43):e31380.
doi: 10.1097/MD.0000000000031380.

Global research trends on precision oncology: A systematic review, bibliometrics, and visualized study

Baoyue Zhang  1 , Bo Ao  2 , Xinyue Lu  3 , Shuang Yang  3 , Pengfei Bao  3 , Hongyun Wang  3 , Ruifeng Li  3 , Youliang Huang  3   4
Affiliations

Global research trends on precision oncology: A systematic review, bibliometrics, and visualized study

Baoyue Zhang et al. Medicine (Baltimore). .

Abstract

Background: Advances in next-generation sequencing technologies are changing the ways cancer diagnosis and treatment, which leads to a new branch of precision medicine: "Precision Oncology". This study aims to deliver a structured overview to carry out a bibliometric analysis of precision oncology research over the past 10 years retrospectively.

Methods: Bibliometric methods including clustering analysis and co-occurrence visualized study were conducted based on publications of academic databases Web of Science Main Collection from 1st January 2012, to 31st December 2021. This study analyzed the information about related research outputs, countries, institutions, authors, cited papers, and hot topics.

Results: 7163 papers related to precision oncology were identified. Since 2014, the number of articles has proliferated, and oncology precision has attracted significant attention from scholars worldwide in recent years. The USA leads the research in this field, and the League of European Research Universities is the primary research institution. Research institutions from Asia paid more attention to this field through high-level international cooperation. Besides, there are still many issues expected to be explored and evaluated correctly. Such as the considerable uncertainty that pharmacogenomic methods have no significant influence on patient outcomes.

Conclusions: Precision oncology serves as an essential method in clinical treatment, and is closely related to biological study, including biochemistry, molecular and genetics, advanced technology, and pharmacology discovery. The future research prospect would be the broad involvement of social participation and global cooperation in oncology precision research to acquire better results via the balance of technology and public health policy.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
Selection process.
Figure 2.
Figure 2.
Annual publication pattern.
Figure 3.
Figure 3.
Worldwide publication distribution.
Figure 4.
Figure 4.
Institutions co-work net of research on oncology precision.
Figure 5.
Figure 5.
Institutions belonged to countries’ collaboration pattern of research on oncology precision.
Figure 6.
Figure 6.
Authors co-work net of research on oncology precision.
Figure 7.
Figure 7.
Top 25 References with the Strongest Citation Bursts.
Figure 8.
Figure 8.
Co-occurrence and clustering network of keywords.
Figure 9.
Figure 9.
Top 25 Timeline view of main topics.
See this image and copyright information in PMC

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