Review
doi: 10.1152/physiol.00022.2022.
Epub 2022 Nov 1.
Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System
Affiliations
- PMID: 36317939
- DOI: 10.1152/physiol.00022.2022
Item in Clipboard
Review
Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System
Physiology (Bethesda).
.
Free article
Abstract
Developmental hypoxia has profound and persistent effects on the vertebrate cardiovascular system, but the nature, magnitude, and long-term outcome of the hypoxic consequences are species specific. Here we aim to identify common and novel cardiovascular responses among vertebrates that encounter developmental hypoxia, and we discuss the possible medical and ecological implications.
Keywords: embryo; fetus; heart; hypoxia; programming.
Similar articles
-
Patterns of form and function in developing hearts: contributions from non-mammalian vertebrates.Cardioscience. 1994 Sep;5(3):183-91. Cardioscience. 1994. PMID: 7827255 Review.
-
The Long-Term Effects of Developmental Hypoxia on Cardiac Mitochondrial Function in Snapping Turtles.Front Physiol. 2021 Jun 28;12:689684. doi: 10.3389/fphys.2021.689684. eCollection 2021. Front Physiol. 2021. PMID: 34262478 Free PMC article.
-
Sildenafil therapy for fetal cardiovascular dysfunction during hypoxic development: studies in the chick embryo.J Physiol. 2017 Mar 1;595(5):1563-1573. doi: 10.1113/JP273393. Epub 2016 Dec 11. J Physiol. 2017. PMID: 27861916 Free PMC article.
-
Cardiovascular development in embryos of the American alligator Alligator mississippiensis: effects of chronic and acute hypoxia.J Exp Biol. 2005 Jan;208(Pt 1):31-9. doi: 10.1242/jeb.01355. J Exp Biol. 2005. PMID: 15601875
-
Time domains of the hypoxic ventilatory response in ectothermic vertebrates.J Comp Physiol B. 2011 Apr;181(3):311-33. doi: 10.1007/s00360-011-0554-6. Epub 2011 Feb 11. J Comp Physiol B. 2011. PMID: 21312038 Free PMC article. Review.
Cited by
-
Maladaptive cardiomyocyte calcium handling in adult offspring of hypoxic pregnancy: protection by antenatal maternal melatonin.J Physiol. 2024 Dec;602(24):6683-6703. doi: 10.1113/JP287325. Epub 2024 Nov 21. J Physiol. 2024. PMID: 39572933 Free PMC article.
-
Impact of late-stage hypoxic stimulation and layer breeder age on embryonic development, hatching and chick quality.Poult Sci. 2025 Feb;104(2):104691. doi: 10.1016/j.psj.2024.104691. Epub 2024 Dec 24. Poult Sci. 2025. PMID: 39731869 Free PMC article.
-
To what extent do physiological tolerances determine elevational range limits of mammals?J Physiol. 2024 Nov;602(21):5475-5484. doi: 10.1113/JP284586. Epub 2023 Oct 27. J Physiol. 2024. PMID: 37889163
-
Developmental plasticity of the cardiovascular system in oviparous vertebrates: effects of chronic hypoxia and interactive stressors in the context of climate change.J Exp Biol. 2024 Oct 15;227(20):jeb245530. doi: 10.1242/jeb.245530. Epub 2024 Aug 7. J Exp Biol. 2024. PMID: 39109475 Free PMC article. Review.
-
Strain-Specific developmental cardiovascular physiology landmarks of embryonic red jungle fowl and black Sumatran bantam chickens (Gallus gallus).Poult Sci. 2025 Aug;104(8):105278. doi: 10.1016/j.psj.2025.105278. Epub 2025 May 9. Poult Sci. 2025. PMID: 40398295 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
