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Review
. 2023 Mar 1;38(2):0.
doi: 10.1152/physiol.00022.2022. Epub 2022 Nov 1.

Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System

Gina L J Galli  1 , Mitchell C Lock  1 , Kerri L M Smith  1 , Dino A Giussani  2 , Dane A Crossley 2nd  3
Affiliations
Free article
Review

Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System

Gina L J Galli et al. Physiology (Bethesda). .
Free article

Abstract

Developmental hypoxia has profound and persistent effects on the vertebrate cardiovascular system, but the nature, magnitude, and long-term outcome of the hypoxic consequences are species specific. Here we aim to identify common and novel cardiovascular responses among vertebrates that encounter developmental hypoxia, and we discuss the possible medical and ecological implications.

Keywords: embryo; fetus; heart; hypoxia; programming.

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