Long COVID: long-term health outcomes and implications for policy and research

Ziyad Al-Aly^{1

2}, Anupam Agarwal³, Nisreen Alwan^{4

5

6}, Valerie A Luyckx^{7

8

9}

Affiliations

¹ Clinical Epidemiology Center, Research and Development Service, VA Saint Louis Health Care System, Saint Louis, MO, USA. zalaly@gmail.com.
² Institute for Public Health, Washington University in Saint Louis, Saint Louis, MO, USA. zalaly@gmail.com.
³ Division of Nephrology, Department of Medicine, University of Alabama School of Medicine, Birmingham, AL, USA.
⁴ School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK.
⁵ NIHR Applied Research Collaboration Wessex, Southampton, UK.
⁶ NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
⁷ Division of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.
⁸ Department of Nephrology, University Children's Hospital Zurich, Zurich, Switzerland.
⁹ Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

PMID: 36319780
PMCID: PMC9628426
DOI: 10.1038/s41581-022-00652-2

Long COVID: long-term health outcomes and implications for policy and research

Ziyad Al-Aly et al. Nat Rev Nephrol. 2023 Jan.

. 2023 Jan;19(1):1-2.

doi: 10.1038/s41581-022-00652-2.

Authors

Ziyad Al-Aly^{1

2}, Anupam Agarwal³, Nisreen Alwan^{4

5

6}, Valerie A Luyckx^{7

8

9}

Affiliations

¹ Clinical Epidemiology Center, Research and Development Service, VA Saint Louis Health Care System, Saint Louis, MO, USA. zalaly@gmail.com.
² Institute for Public Health, Washington University in Saint Louis, Saint Louis, MO, USA. zalaly@gmail.com.
³ Division of Nephrology, Department of Medicine, University of Alabama School of Medicine, Birmingham, AL, USA.
⁴ School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK.
⁵ NIHR Applied Research Collaboration Wessex, Southampton, UK.
⁶ NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
⁷ Division of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.
⁸ Department of Nephrology, University Children's Hospital Zurich, Zurich, Switzerland.
⁹ Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

PMID: 36319780
PMCID: PMC9628426
DOI: 10.1038/s41581-022-00652-2

Abstract

Long COVID, which refers to post-acute and chronic sequelae of SARS-CoV-2 infection, can affect nearly every organ system and all demographic groups. The high and growing toll of long COVID calls for an urgent need to understand how to prevent and treat it. Governments and health systems must address the care needs of people with long COVID.

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Conflict of interest statement

The authors declare no competing interests.

References

1. Alwan NA. The road to addressing long Covid. Science. 2021;373:491–493. doi: 10.1126/science.abg7113. - DOI - PubMed
1. Xie Y, Bowe B, Al-Aly Z. Burdens of post-acute sequelae of COVID-19 by severity of acute infection, demographics and health status. Nat. Commun. 2021;12:6571. doi: 10.1038/s41467-021-26513-3. - DOI - PMC - PubMed
1. Al-Aly Z, Xie Y, Bowe B. High-dimensional characterization of post-acute sequelae of COVID-19. Nature. 2021;594:259–264. doi: 10.1038/s41586-021-03553-9. - DOI - PubMed
1. Bowe B, Xie Y, Xu E, Al-Aly Z. Kidney outcomes in long COVID. J. Am. Soc. Nephrol. 2021;32:2851–2862. doi: 10.1681/ASN.2021060734. - DOI - PMC - PubMed
1. Nugent J, et al. Assessment of acute kidney injury and longitudinal kidney function after hospital discharge among patients with and without COVID-19. JAMA Netw. Open. 2021;4:e211095. doi: 10.1001/jamanetworkopen.2021.1095. - DOI - PMC - PubMed

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Long COVID: long-term health outcomes and implications for policy and research

Affiliations

Long COVID: long-term health outcomes and implications for policy and research

Authors

Affiliations

Abstract

Conflict of interest statement

References

MeSH terms

LinkOut - more resources

Full Text Sources

Medical

Miscellaneous