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Comment
. 2022 Nov 1;34(11):1611-1613.
doi: 10.1016/j.cmet.2022.10.006.

Out of destruction comes new growth: Pore-forming antimicrobials make pancreas grow

Rebecca Yunker  1 , Maryam Bonakdar  1 , Shipra Vaishnava  2
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Out of destruction comes new growth: Pore-forming antimicrobials make pancreas grow

Rebecca Yunker et al. Cell Metab. .
Free article

Abstract

Gut-residing bacteria are known to regulate the physiologies of distal organs. However, the mechanism behind the long-distance communication between gut microbes and distal organs remains unknown. In this issue of Cell Metabolism, two studies show that β cell expansion in the pancreas depends on bacterially induced antimicrobials produced in the gut.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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