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. 2022 Nov 4;22(1):376.
doi: 10.1186/s12893-022-01824-4.

Subtotal gastrectomy pancreaticoduodenectomy versus conventional pancreaticoduodenectomy in the incidence of delayed gastric emptying: single-center retrospective cohort study

Jinzhu Zhang  1 , Shu Li  1 , Weihua Zhu  1 , Xisheng Leng  1 , Jie Gao  2 , Dafang Zhang  3
Affiliations

Subtotal gastrectomy pancreaticoduodenectomy versus conventional pancreaticoduodenectomy in the incidence of delayed gastric emptying: single-center retrospective cohort study

Jinzhu Zhang et al. BMC Surg. .

Abstract

Background: Delayed gastric emptying (DGE) is one of the most common complications after pancreaticoduodenectomy (PD). There is currently no widely accepted procedure for PD to reduce the incidence of DGE. Our institution attempts to perform subtotal gastrectomy in patients undergoing PD to reduce DGE. Here we aimed to evaluate the effectiveness and safety of PD with subtotal gastric resection.

Methods: Patients who underwent PD between January 2014 and December 2021 were reviewed. They were stratified by extent of gastrectomy into a conventional PD group (PD that resected approximately 1/3 of the distal stomach) and a subtotal gastrectomy PD group (PD that resected approximately 3/4 of the distal stomach), which were compared in terms of intraoperative and postoperative parameters.

Result: From January 2014 to December 2021, a total of 512 patients underwent PD in the Department of Hepatobiliary Surgery, Peking University People's Hospital. Nineteen patients were excluded from this study due to benign disease. A total of 493 patients were included, with 378 in the conventional PD group and 115 in the subtotal gastrectomy PD group. Compared with the conventional PD group, the subtotal gastrectomy PD group had a lower incidence of DGE (8.7% vs. 17.7%, p = 0.019), and a shorter hospital stay. Multivariate analysis showed that conventional PD and higher body mass index were independent risk factors for grade B/C DGE.

Conclusion: This study showed that, compared with conventional PD, subtotal gastrectomy PD can reduce the incidence of DGE and shorten the length of hospital stay. At the same time, subtotal gastrectomy PD is comparable to conventional PD in terms of surgical safety. Furthermore, high BMI is an independent risk factor for postoperative DGE.

Keywords: Complication; Delayed gastric emptying; General surgery; Pancreaticoduodenectomy; Subtotal gastrectomy; Surgery.

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Conflict of interest statement

All authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Illustration of the two PD. a Conventional PD removes approximately 1/3 of the distal end of the stomach. The resection line for the stomach is located just above the gastric antrum. b Subtotal gastrectomy PD removes the distal 3/4 of the stomach. The resection line crosses the second branch of the left gastric artery and the avascular area on the left side of the stomach
See this image and copyright information in PMC

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