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Editorial
. 2022 Oct;10(19):1045.
doi: 10.21037/atm-2022-31.

Shining a light on foveal development after congenital cataract surgery

Annegret Dahlmann-Noor  1 , Maryse Bailly  2
Affiliations
Editorial

Shining a light on foveal development after congenital cataract surgery

Annegret Dahlmann-Noor et al. Ann Transl Med. 2022 Oct.
No abstract available

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Conflict of interest statement

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://atm.amegroups.com/article/view/10.21037/atm-2022-31/coif). ADN is supported by the National Institute for Health Research (NIHR) Moorfields Biomedical Research Centre. Her institution has received research funding from Moorfields Eye Charity. She has served as medical advisor for Santen, Thea and Sight Glass Vision, and has participated in and prepared educational activities and events for Santen, Cooper Vision and Novartis. The other author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Proposed postnatal mechanisms of cone packing. Light (yellow arrow) may trigger radial contraction of cone photoreceptors inner segments (light green), horizontal contraction of Müller cells (light blue block lines), contraction of RPE cells (light orange) and/or choroidal NVSMCs (pink lines), thereby increasing foveal cone density. Molecular mechanisms may include light-triggered release of growth factors, cytokines and angiogenic factors by photoreceptors and RPE cells. Congenital cataract may impact on foveal cone packing and maturation by disrupting these pathways. Diagrams drawn using Motifolio Biomedical Diagrams. RPE, retinal pigment epithelial; NVSMCs, non-vascular smooth muscle cells.
See this image and copyright information in PMC

Comment on

References

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