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. 2022 Jan;64(1):e15337.
doi: 10.1111/ped.15337.

Efficacy of anakinra on rebound of multisystem inflammatory syndrome

Giacomo Brisca  1 , Camilla Olcese  2 , Maria Elena Derchi  3 , Gianluca Trocchio  3 , Roberta Caorsi  4 , Andrea Moscatelli  1 , Marco Gattorno  4   5
Affiliations

Efficacy of anakinra on rebound of multisystem inflammatory syndrome

Giacomo Brisca et al. Pediatr Int. 2022 Jan.
No abstract available

Keywords: MIS-C; SARS-CoV-2; acute pericarditis; anakinra; multisystem inflammatory syndrome in children.

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Figures

Fig. 1
Fig. 1
Disease flares, C‐reactive protein levels (CRP), therapeutic interventions with IV immunoglobulin, and Anakinra (panel a), and steroids (panel b) during the disease course. (formula image), prednisone; (formula image), methylprednisolone.
See this image and copyright information in PMC

References

    1. Henderson LA, Canna SW, Friedman KG et al. American College of Rheumatology Clinical Guidance for multisystem inflammatory syndrome in children associated with SARS‐CoV‐2 and hyperinflammation in pediatric COVID‐19: Version 2. Arthritis Rheumatol. 2021; 73: e13–29. - PMC - PubMed
    1. Feldstein LR, Tenforde MW, Friedman KG et al. Characteristics and outcomes of US children and adolescents with multisystem inflammatory syndrome in children (MIS‐C) compared with severe acute COVID‐19. JAMA 2021; 325 (11): 1074–87. - PMC - PubMed
    1. Pawar RS, Tarkasband VA, Patil RK, Naik AV. Second episode of multisystem inflammatory syndrome in children: Relapse, rebound, or recurrence? Pediatr. Infect. Dis. J. 2021; 40: e452. - PubMed
    1. Brisca G, Consolaro A, Caorsi R et al. Timely recognition and early multi‐step Antinflammatory therapy may prevent ICU admission of patients with MIS‐C: Proposal for a severity score. Front. Pediatr. 2021; 20: 783745. - PMC - PubMed
    1. Nuffield Department of Population Health . Information for site staff (homepage on the Internet). [Cited 18 May 2022]. Available from URL: https://www.recoverytrial.net/for‐site‐staff

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