Gutsy memory T cells stand their ground against pathogens

Abstract

Elegant fate-mapping models to label intestinal tissue-resident memory CD8⁺ T (T_RM) cells demonstrate retention and lack of expansion of CD103⁺ T_RM cells, whereas intestinal CD103^- memory cells expand, forming both new tissue-localized CD103⁺ and CD103^- T_RM cells (see related Research Articles by Fung et al. and von Hoesslin et al.).