Taking the STING out
- PMID: 36332010
- DOI: 10.1126/sciimmunol.adf5127
Taking the STING out
Abstract
ABCC1 is an ATP-dependent cGAMP exporter responsible for negatively regulating STING signaling.
Comment on
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ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP.Immunity. 2022 Oct 11;55(10):1799-1812.e4. doi: 10.1016/j.immuni.2022.08.006. Epub 2022 Sep 6. Immunity. 2022. PMID: 36070769 Free PMC article.
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