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Comment
. 2022 Nov 3;82(21):3963-3965.
doi: 10.1016/j.molcel.2022.10.006.

TERRA and RAD51AP1 at the R&D-loop department of ALT telomeres

Anabelle Decottignies  1
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TERRA and RAD51AP1 at the R&D-loop department of ALT telomeres

Anabelle Decottignies. Mol Cell. .
Free article

Abstract

In this issue of Molecular Cell, Kaminski et al. and Yadav et al. demonstrate that RAD51AP1 and TERRA non-coding RNA positively regulate the alternative mechanism of telomere maintenance by promoting D-loop formation and chromatin-directed mechanisms to suppress transcription-collision events during ALT telomere synthesis.

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Declaration of interests The author declares no competing interests.

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