Novel "Thetis" antigen-presenting cells promote early life gut immune tolerance

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Alkeiver S Cannon et al. Immunol Cell Biol. 2023 Jan.

. 2023 Jan;101(1):16-19.

doi: 10.1111/imcb.12605. Epub 2022 Nov 22.

¹ Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

No abstract available

Keywords: Treg; antigen-presenting cells (APCs); gut microbiota; immune tolerance.

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Novel antigen-presenting cell imparts T_reg-dependent tolerance to gut microbiota.
Akagbosu B, Tayyebi Z, Shibu G, Paucar Iza YA, Deep D, Parisotto YF, Fisher L, Pasolli HA, Thevin V, Elmentaite R, Knott M, Hemmers S, Jahn L, Friedrich C, Verter J, Wang ZM, van den Brink M, Gasteiger G, Grünewald TGP, Marie JC, Leslie C, Rudensky AY, Brown CC. Akagbosu B, et al. Nature. 2022 Oct;610(7933):752-760. doi: 10.1038/s41586-022-05309-5. Epub 2022 Sep 7. Nature. 2022. PMID: 36070798 Free PMC article.

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