Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jan;415(1):17-25.
doi: 10.1007/s00216-022-04392-x. Epub 2022 Nov 5.

Lab at home: a promising prospect for on-site chemical and biological analysis

Affiliations

Lab at home: a promising prospect for on-site chemical and biological analysis

Jian-Zhang Pan et al. Anal Bioanal Chem. 2023 Jan.

Abstract

The continuing pursuit for a healthy life has led to the urgent need for on-site analysis. In response to the urgent needs of on-site analysis, we propose a novel concept, called lab at home (LAH), for building automated and integrated total analysis systems to perform chemical and biological testing at home. It represents an emerging research area with broad prospects that has not yet attracted sufficient attention. In this paper, we discuss the urgent need, challenges, and future prospects of this area, and the possible roadmap for achieving the goal of LAH has also been proposed.

Keywords: Biochemical analysis; Lab at Home; Microfluidic analysis; On-site analysis.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Milestone diagram of some nodal technique in the development of POCT and microfluidic chips
Fig. 2
Fig. 2
Conceptual diagram of the composition and application of Lab-at-Home systems
Fig. 3
Fig. 3
Microfluidic liquid-handling techniques with potentials to meet the requirements of a household analyzer in high versatility and complex manipulation ability. a Centrifugation control; b Micropump/microvalve; c Digital microfluidics; and d Sequential operation droplet array (SODA)

References

    1. Luppa PB, Müller C, Schlichtiger A, Schlebusch H. Point-of-care testing (POCT): current techniques and future perspectives. TrAC-Trend Anal Chem. 2011;30:887–898. doi: 10.1016/j.trac.2011.01.019. - DOI - PMC - PubMed
    1. Livak-Dahl E, Sinn I, Burns M. Microfluidic chemical analysis systems. Annu Rev Chem Biomol. 2011;2:325–353. doi: 10.1146/annurev-chembioeng-061010-114215. - DOI - PubMed
    1. Srinivasan B, Tung S. Development and applications of portable biosensors. J Lab Autom. 2015;20:365–389. doi: 10.1177/2211068215581349. - DOI - PubMed
    1. Wagar EA, Yasin B, Yuan S. Point-of-care testing: twenty years’ experience. Lab Med. 2008;39:560–563. doi: 10.1309/9R9Y0V68Y3BA0KDN. - DOI
    1. Lu F, Yang SS, Ning Y, Wang FB, Ji XH, He ZK. A fluorescence color card for point-of-care testing (POCT) and its application in simultaneous detection. Analyst. 2021;146:5074–5080. doi: 10.1039/d1an01035b. - DOI - PubMed

LinkOut - more resources