Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Mar;40(3):e15000.
doi: 10.1111/dme.15000. Epub 2022 Nov 16.

Reproducibility of plasma glucose responses to moderate-intensity exercise in individuals with type 1 diabetes

Wayne H K Soon  1   2   3 , Paul A Fournier  2 , Mary B Abraham  1   3   4 , Grant J Smith  3 , Nirubasini Paramalingam  1   2   3   4 , Vinutha B Shetty  1   2   3   4 , Kym J Guelfi  2 , Timothy W Jones  1   3   4 , Elizabeth A Davis  1   3   4
Affiliations

Reproducibility of plasma glucose responses to moderate-intensity exercise in individuals with type 1 diabetes

Wayne H K Soon et al. Diabet Med. 2023 Mar.

Abstract

Aim: To examine the within-person variability in plasma glucose responses to moderate-intensity morning exercise in young individuals with type 1 diabetes after overnight fasting and under basal insulin conditions.

Methods: In this pilot study, eight participants completed 40 min of moderate-intensity exercise at 60% V̇O2 peak on three separate days. The within-person standard deviation (SDw) in plasma glucose response was analysed both during and 1 h after exercise using the two visits per participant most closely matched by pre-exercise plasma glucose level.

Results: When the two closest matched visits per individual were included for analysis, mean (±SD) change in plasma glucose level was -1.8 ± 1.1 mmoL/L during exercise and -0.6 ± 1.0 mmoL/L during recovery, with the SDw of these changes being 0.5 mmol (95% CI 0.2, 0.8) during exercise and 0.8 mmoL/L (95% CI 0.4, 1.3) during recovery. The median intra-individual difference in plasma glucose level change was 0.3 mmoL/L [IQR 0.1, 0.7] during exercise and 0.8 mmoL/L [IQR 0.4, 1.0] during recovery.

Conclusion: Within-person plasma glucose responses to moderate-intensity exercise may be reproducible under fasting and basal insulin conditions and similar pre-exercise plasma glucose levels. This finding may assist the design of future studies investigating both the reproducibility of glycaemic responses to exercise and blood glucose management for individuals with type 1 diabetes.

Keywords: exercise; reproducibility; type 1 diabetes.

PubMed Disclaimer

References

REFERENCES

    1. Colberg SR, Laan R, Dassau E, Kerr D. Physical activity and type 1 diabetes: time for a rewire? J Diabetes Sci Technol. 2015;9(3):609-618.
    1. Galassetti P, Riddell MC. Exercise and type 1 diabetes (T1DM). Compr Physiol. 2013;3(3):1309-1336.
    1. Riddell MC, Taplin CE. Exercise in children with type 1 diabetes. In: Scaramuzza A, de Beaufort C, Hanas R, eds. Research into Childhood-Onset Diabetes: from Study Design to Improved Management. Springer International Publishing; 2017:77-89.
    1. Wiesinger GF, Pleiner J, Quittan M, et al. Health related quality of life in patients with long-standing insulin dependent (type 1) diabetes mellitus: benefits of regular physical training. Wien Klin Wochenschr. 2001;113(17-18):670-675.
    1. Jabbour G, Henderson M, Mathieu ME. Barriers to active lifestyles in children with type 1 diabetes. Can J Diabetes. 2016;40(2):170-172.

Publication types

LinkOut - more resources