Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Jun 30;2022(1-2):e202206.
doi: 10.21542/gcsp.2022.6.

Takotsubo cardiomyopathy secondary to alcohol withdrawal

Affiliations
Case Reports

Takotsubo cardiomyopathy secondary to alcohol withdrawal

Faizan Ahmed et al. Glob Cardiol Sci Pract. .

Abstract

Physical, mental, and emotional stressors have been well known to adversely affect cardiac function. A rare complication of such stressors is stress cardiomyopathy, otherwise known as takotsubo cardiomyopathy. First identified in Japan in the 1990s, takotsubo cardiomyopathy classically presents with systolic dysfunction and apical ballooning. In this report, we present the case of a patient with a medical history of alcohol abuse who presented to the emergency department after being found unresponsive by her family. Transthoracic echocardiography revealed takotsubo cardiomyopathy, which was likely secondary to alcohol withdrawal. Alcohol withdrawal causes an imbalance between various neurotransmitters such as GABA and glutamate. This imbalance caused autonomic overactivity, which manifested as stress cardiomyopathy.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. RAO caudal views revealing no significant coronary artery disease of the left-sided coronary arteries.
Figure 2.
Figure 2.. LAO cranial view revealing no significant coronary artery disease of the right-sided coronary arteries.

References

    1. Kurowski V, Kaiser A, von Hof K, Killermann DP, Mayer B, Hartmann F, Schunkert H, Radke PW. Apical and midventricular transient left ventricular dysfunction syndrome (tako-tsubo cardiomyopathy): frequency, mechanisms, and prognosis. Chest. 2007;132(3):809–816. doi: 10.1378/chest.07-0608. doi: - DOI - PubMed
    1. Bybee KA, Prasad A. Stress-related cardiomyopathy syndromes. Circulation. 2008;118(4):397–409. doi: 10.1161/CIRCULATIONAHA.106.677625. doi: - DOI - PubMed
    1. Scantlebury DC, Prasad A. Diagnosis of Takotsubo cardiomyopathy. Circ J. 2014;78(9):2129–2139. doi: 10.1253/circj.CJ-14-0859. doi: - DOI - PubMed
    1. Nef HM, Möllmann H, Akashi YJ, Hamm CW. Mechanisms of stress (Takotsubo) cardiomyopathy. Nat Rev Cardiol. 2010;7(4):187–193. doi: 10.1038/nrcardio.2010.16. doi: - DOI - PubMed
    1. Schiano P, Revel F, Barbou F, Guiraudet O, Lerecouvreux M, Monségu J. Cardiac toxicity of catecholamines. Report of two cases. Rev Med Interne. 2007;28(12):866–870. doi: 10.1016/j.revmed.2007.06.009. doi: - DOI - PubMed

Publication types

LinkOut - more resources