Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Oct 30:15:2335-2343.
doi: 10.2147/CCID.S381380. eCollection 2022.

Long-Term Use of Antiperspirant is Associated with a Low Risk of Postoperative Complications in Patients with Axillary Osmidrosis

Wen-Tsao Ho #  1 , Chin-Yi Yang #  2   3   4 , Ming-Feng Tsai  5   6   7
Affiliations

Long-Term Use of Antiperspirant is Associated with a Low Risk of Postoperative Complications in Patients with Axillary Osmidrosis

Wen-Tsao Ho et al. Clin Cosmet Investig Dermatol. .

Abstract

Purpose: Many patients with axillary osmidrosis (AO) cannot tolerate the local irritation of strong antiperspirants and discontinue AO use within a short time. This study evaluates the effect of long-term antiperspirant use on postoperative complications after osmidrosis surgery.

Patients and methods: A total of 116 females (66 antiperspirant and 50 non-antiperspirant cases) who underwent osmidrosis surgery were retrospectively reviewed. Postoperative complications were compared between the 2 groups.

Results: Patients with long-term antiperspirant use had a lower risk of full-thickness skin necrosis compared with those who did not use antiperspirants (odds ratio [OR] = 0.048, 95% confidence Interval [CI]: 0.006-0.392, p = 0.005). Patients with antiperspirants use also had a lower risk of moderate-to-severe erythema compared to those without antiperspirants use (moderate vs mild erythema: OR = 0.351, 95% CI: 0.129-0.959, p = 0.041; severe vs mild erythema: OR = 0.161, 95% CI: 0.047-0.550, p = 0.004). Patients who used antiperspirants also had a lower risk of severe skin erosion compared to those who did not use antiperspirants (severe vs mild skin erosion: OR = 0.164, 95% CI: 0.037-0.725, p = 0.017). There was a trend of lower risk in moderate skin erosion in patients with antiperspirant use compared to those without antiperspirant use, but it was not statistically significant (moderate vs mild epidermal damage and peeling: OR = 0.406, 95% CI: 0.158-1.043, p = 0.061).

Conclusion: Postoperative complications in patients with AO who undergo osmidrosis surgery are lower in those with a long-term antiperspirant use compared to patients who did not use antiperspirants.

Keywords: antiperspirant; axillary osmidrosis; complications; surgery.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Complications in antiperspirant and non-antiperspirant groups. (A) Upper panel, figure showed a 28-year-old woman without prior antiperspirant use who had mild erythema, moderate skin erosion, and full-thickness skin necrosis and lower panel, figure showed a 30-year-old woman without prior antiperspirant use who had mild erythema, severe skin erosion, and full-thickness skin necrosis. (B) Upper (24-year-old woman) and lower (30-year-old woman) panels, figures showed patients with prior antiperspirant use who had mild postoperative erythema and skin erosion.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Dong Z, Tan Z, Chen Z. Association of BMI and lipid profiles with axillary osmidrosis: a retrospective case-control study. J Dermatolog Treat. 2021;32(6):654–657. doi:10.1080/09546634.2019.1688232 - DOI - PubMed
    1. Zhang L, Chen F, Kong J, Li Z, Wen X, Liu J. The curative effect of liposuction curettage in the treatment of bromhidrosis: a meta-analysis. Medicine. 2017;96(33):e7844. doi:10.1097/MD.0000000000007844 - DOI - PMC - PubMed
    1. Morioka D, Ohkubo F, Amikura Y. Clinical features of axillary osmidrosis: a retrospective chart review of 723 Japanese patients. J Dermatol. 2013;40(5):384–388. doi:10.1111/1346-8138.12115 - DOI - PubMed
    1. Shin JY, Roh SG, Lee NH, Yang KM. Osmidrosis treatment approaches: a systematic review and meta-analysis. Ann Plast Surg. 2017;78(3):354–359. doi:10.1097/SAP.0000000000000911 - DOI - PubMed
    1. Wang R, Yang J, Sun J, Minimally Invasive A. Procedure for axillary osmidrosis: subcutaneous curettage combined with trimming through a small incision. Aesthetic Plast Surg. 2015;39(1):106–113. doi:10.1007/s00266-014-0431-2 - DOI - PubMed