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. 2020 Jun 12;5(Pt 6):x200759.
doi: 10.1107/S2414314620007592. eCollection 2020 Jun.

(E)-2-(3,5-Di-meth-oxy-benzyl-idene)indan-1-one

Elvia Encarnacion-Thomas  1 , Roger D Sommer  2 , Ajay Mallia  1 , Joseph Sloop  1
Affiliations

(E)-2-(3,5-Di-meth-oxy-benzyl-idene)indan-1-one

Elvia Encarnacion-Thomas et al. IUCrdata. .

Abstract

The title chalcone, C18H16O3, was prepared by a solventless base-promoted Claisen-Schmidt condensation and, upon recrystallization from ethanol, obtained in 56% yield. The dihedral angle between the indanone ring system and the benzene ring is 2.54 (4) ° and the C atoms of the methoxy groups deviate from the benzene ring by 0.087 (1) and 0.114 (1) Å. In the crystal, π-stacking is the predominant inter-molecular force, with the mol-ecules stacking into columns running parallel to the b axis of the unit cell.

Keywords: chalcone; crystal structure; green synthesis; indanone.

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Figures

Figure 1
Figure 1
Green synthesis scheme for indanone-based chalcones
Figure 2
Figure 2
Displacement ellipsoid plot of 1b. Ellipsoids are drawn at the 50% probability level.
Figure 3
Figure 3
Packing diagram of 1b viewed along the b axis.
See this image and copyright information in PMC

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