Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Oct 11;4(3):178-181.
doi: 10.3138/jammi.2019-04-12. eCollection 2019 Oct.

Cryptococcemia presenting as an opportunistic infection due to chronic visceral leishmaniasis

Kathleen Gregory-Miller  1 , Zain Chagla  1 , Deborah Yamamura  2 , Philippe El-Helou  1
Affiliations
Case Reports

Cryptococcemia presenting as an opportunistic infection due to chronic visceral leishmaniasis

Kathleen Gregory-Miller et al. J Assoc Med Microbiol Infect Dis Can. .

Abstract
in English, French

We present a case of visceral leishmaniasis (VL) in a previously immunocompetent patient. At the time of presentation, he was co-infected with Cryptococcus neoformans. This case demonstrates how infectious diseases besides human immunodeficiency virus can lead to immunosuppression for patients, placing them at risk of opportunistic infections.

Les auteurs présentent le cas d’une leishmaniose viscérale (LV) chez un patient auparavant immunocompétent. Au moment de consulter, il était co-infecté par un Cryptococcus neoformans. Ce cas démontre que, conjuguées au virus d’immunodéficience humaine, les maladies infectieuses peuvent provoquer une immunosuppression et rendre les patients vulnérables à des infections opportunistes.

Keywords: Cryptococcus; co-infection; leishmaniasis; opportunistic infection.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
On Hematoxylin and Eosin stains, the bone marrow biopsy showed increased histiocytes with cytoplasmic filling by 1.7–2.0 micron-sized organisms identified as Leishmania
See this image and copyright information in PMC

References

    1. Awasthi A,Mathur RK,Saha B. Immune response to Leishmania infection. Indian J Med Res. 2004;119(6):238–58. Medline: - PubMed
    1. van Griensven J,Diro E. Visceral leishmaniasis. Infect Dis Clin North Am. 2012;26(2):309–22. 10.1016/j.idc.2012.03.005. Medline: - DOI - PubMed
    1. Cota GF,Gomes LI,Pinto BR, et al. Dyarrheal syndrome in a patient co-infected with Leishmania infantum and Schistosoma manosoni. Case Rep Med. 2012:Article ID 240512. 10.1155/2012/240512. Medline: - DOI - PMC - PubMed
    1. Kozubowski L,Heitman J, Profiling a killer the development of Cryptococcus neoformans. FEMS Microbiol Rev. 2012;36(1):78–94. 10.1111/j.1574-6976.2011.00286.x. Medline: - DOI - PMC - PubMed
    1. Hofman V,Brousset P,Mougneau E, et al. Immunostaining of visceral leishmaniasis caused by Leishmania infantum using monoclonal antibody (19–11) to the Leishmania homologue of receptors for activated C-kinase. Am J Clin Pathol. 2013;120(4):567–74. 10.1309/R3DK4MR3W6E5PH17. Medline: - DOI - PubMed

Publication types

LinkOut - more resources