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Review
. 2022 Sep;18(3):220151.
doi: 10.1183/20734735.0151-2022. Epub 2022 Oct 11.

Recent advances in paediatric sleep disordered breathing

Affiliations
Review

Recent advances in paediatric sleep disordered breathing

Alison J B Garde et al. Breathe (Sheff). 2022 Sep.

Abstract

This article reviews the latest evidence pertaining to childhood sleep disordered breathing (SDB), which is associated with negative neurobehavioural, cardiovascular and growth outcomes. Polysomnography is the accepted gold standard for diagnosing SDB but is expensive and limited to specialist centres. Simpler tests such as cardiorespiratory polygraphy and pulse oximetry are probably sufficient for diagnosing obstructive sleep apnoea (OSA) in typically developing children, and new data-processing techniques may improve their accuracy. Adenotonsillectomy is the first-line treatment for OSA, with recent evidence showing that intracapsular tonsillectomy results in lower rates of adverse events than traditional techniques. Anti-inflammatory medication and positive airway pressure respiratory support are not always suitable or successful, although weight loss and hypoglossal nerve stimulation may help in select comorbid conditions.

Educational aims: To understand the clinical impact of childhood sleep disordered breathing (SDB).To understand that, while sleep laboratory polysomnography has been the gold standard for diagnosis of SDB, other diagnostic techniques exist with their own benefits and limitations.To recognise that adenotonsillectomy and positive pressure respiratory support are the mainstays of treating childhood SDB, but different approaches may be indicated in certain patient groups.

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Conflict of interest statement

Conflict of interest: A.J.B. Garde has nothing to disclose. Conflict of interest: N.A. Gibson has nothing to disclose. Conflict of interest: M.P. Samuels has nothing to disclose. Conflict of interest: H.J. Evans has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
Continuous positive airway pressure trace showing frequent pressure changes with autotitration. SpO2: peripheral oxygen saturation; PtcCO2: transcutaneous carbon dioxide tension.

References

    1. Ucros S, Granados C, Hill C, et al. . Normal values for respiratory sleep polygraphy in children aged 4 to 9 years at 2,560 m above sea level. J Sleep Res 2021; 30: e13341. doi:10.1111/jsr.13341 - DOI - PubMed
    1. Hill CM, Evans HJ, Elphick H, et al. . Prevalence and predictors of obstructive sleep apnoea in young children with Down syndrome. Sleep Med 2016; 27–28: 99–106. doi:10.1016/j.sleep.2016.10.001 - DOI - PubMed
    1. Kaditis AG, Alonso Alvarez ML, Boudewyns A, et al. . Obstructive sleep disordered breathing in 2- to 18-year-old children: diagnosis and management. Eur Respir J 2016; 47: 69–94. doi:10.1183/13993003.00385-2015 - DOI - PubMed
    1. Musso MF, Lindsey HM, Wilde EA, et al. . Volumetric brain magnetic resonance imaging analysis in children with obstructive sleep apnea. Int J Pediatr Otorhinolaryngol 2020; 138: 110369. doi:10.1016/j.ijporl.2020.110369 - DOI - PubMed
    1. Mei L, Li X, Zhou G, et al. . Effects of obstructive sleep apnoea severity on neurocognitive and brain white matter alterations in children according to sex: a tract-based spatial statistics study. Sleep Med 2021; 82: 134–143. doi:10.1016/j.sleep.2020.08.026 - DOI - PubMed

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