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Editorial
. 2023 Mar 15;207(6):649-651.
doi: 10.1164/rccm.202210-2000ED.

Adequate Antimicrobial Dosing in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation: Where to Go from Here?

Isabel Spriet  1   2 , Jan J De Waele  3   4
Affiliations
Editorial

Adequate Antimicrobial Dosing in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation: Where to Go from Here?

Isabel Spriet et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Antimicrobial dosing strategy in patients treated with ECMO with or without RRT. AKI = acute kidney injury; CKD = chronic kidney disease; ECMO = extracorporeal membrane oxygenation; mCrCI = measured creatinine clearance; RRT = renal replacement therapy.
See this image and copyright information in PMC

Comment on

  • Antimicrobial Exposures in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation.
    Shekar K, Abdul-Aziz MH, Cheng V, Burrows F, Buscher H, Cho YJ, Corley A, Diehl A, Gilder E, Jakob SM, Kim HS, Levkovich BJ, Lim SY, McGuinness S, Parke R, Pellegrino V, Que YA, Reynolds C, Rudham S, Wallis SC, Welch SA, Zacharias D, Fraser JF, Roberts JA. Shekar K, et al. Am J Respir Crit Care Med. 2023 Mar 15;207(6):704-720. doi: 10.1164/rccm.202207-1393OC. Am J Respir Crit Care Med. 2023. PMID: 36215036 Clinical Trial.

References

    1. World Health Organization. 2021. https://apps.who.int/iris/handle/10665/341666
    1. Roberts JA, Paul SK, Akova M, Bassetti M, De Waele JJ, Dimopoulos G, et al. DALI Study DALI: defining antibiotic levels in intensive care unit patients. Are current β-lactam antibiotic doses sufficient for critically ill patients? Clin Infect Dis . 2014;58:1072–1083. - PubMed
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    1. Sherwin J, Heath T, Watt K. Pharmacokinetics and dosing of anti-infective drugs in patients on extracorporeal membrane oxygenation: a review of the current literature. Clin Ther . 2016;38:1976–1994. - PMC - PubMed

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