Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review

Minimally Invasive Esophagectomy for Esophageal Cancer

In: Gastrointestinal Cancers [Internet]. Brisbane (AU): Exon Publications; 2022 Sep 30. Chapter 9.
Affiliations
Free Books & Documents
Review

Minimally Invasive Esophagectomy for Esophageal Cancer

Livia Palmieri et al.
Free Books & Documents

Excerpt

Esophageal cancer is currently the eighth most common cancer, and the sixth leading cause of death from cancer in the world due to its highly aggressive nature. Better prognosis can be achieved with early diagnosis in early stages of the disease. The increasing incidence rate and the distribution of esophageal cancer varies with tumor type location and with geographical area. Multiple factors like ethnicity, genetic factors, and lifestyle play a role. Currently, Barrett’s esophagus is still the only known precursor. Due to its natural history, esophageal cancer is commonly diagnosed in more advanced stages. In tumors confined to the mucosa, local endoscopic treatment is considered curative whereas when the tumor invades the submucosa, surgical esophagectomy is the current standard treatment. In case of locally advanced disease, neoadjuvant chemo or chemo-radio therapy is now considered the gold standard treatment. The advent of minimally invasive surgical techniques has reduced morbidity and mortality of esophagectomy without compromising the oncological outcomes. In the chapter, the McKeown mini-invasive esophagectomy technique is described.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: The authors declare no potential conflict of interest with respect to research, authorship and/or publication of this chapter.

References

    1. Enzinger PC, Mayer RJ. Esophageal Cancer. N Engl J Med. 2003;349(23):2241–52. https://doi.org/10.1056/NEJMra035010 . - DOI - PubMed
    1. Pennathur A, Gibson MK, Jobe BA, Luketich JD. Oesophageal carcinoma. Lancet. 2013;381(9864):400–12. https://doi.org/10.1016/S0140-6736(12)60643-6 . - DOI - PubMed
    1. Umar SB, Fleischer DE. Esophageal cancer: Epidemiology, pathogenesis and prevention. Nat Clin Pract Gastroenterol Hepatol. 2008;5(9):517–26. https://doi.org/10.1038/ncpgasthep1223 . - DOI - PubMed
    1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. A Cancer J Clin. 2011;61(2):69–90. https://doi.org/10.3322/caac.20107 . - DOI - PubMed
    1. Sharma P, McQuaid K, Dent J, Fennerty MB, Sampliner R, Spechler S, et al. A critical review of the diagnosis and management of Barrett’s esophagus: The AGA Chicago Workshop. Gastroenterology. 2004;127(1):310–30. https://doi.org/10.1053/j.gastro.2004.04.010 . - DOI - PubMed

LinkOut - more resources