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Case Reports
. 2022 Nov 7;15(11):e252814.
doi: 10.1136/bcr-2022-252814.

Bisphosphonate therapy for juvenile dermatomyositis-associated calcinosis and metaphyseal zebra lines

Mahesh Janarthanan  1 , Meenakshi Mohan  2 , Arunan Murali  3
Affiliations
Case Reports

Bisphosphonate therapy for juvenile dermatomyositis-associated calcinosis and metaphyseal zebra lines

Mahesh Janarthanan et al. BMJ Case Rep. .
No abstract available

Keywords: Connective tissue disease; Drugs: musculoskeletal and joint diseases.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
X-ray of the lower abdomen and pelvis showing extensive calcinosis.
Figure 2
Figure 2
X-ray of the pelvis and thighs showing extensive calcinosis.
Figure 3
Figure 3
MRI of the thighs showing muscle oedema and calcification.
Figure 4
Figure 4
X-ray of the pelvis and lower abdomen after treatment shows resolution of calcinosis.
Figure 5
Figure 5
X-ray of the lower limbs after treatment showing remnant calcinosis and zebra lines (arrows pointing to zebra lines).
See this image and copyright information in PMC

References

    1. Hoeltzel MF, Oberle EJ, Robinson AB, et al. . The presentation, assessment, pathogenesis, and treatment of calcinosis in juvenile dermatomyositis. Curr Rheumatol Rep 2014;16:467. 10.1007/s11926-014-0467-y - DOI - PMC - PubMed
    1. Twilt M, Feldman BM. An update on the diagnosis and management of juvenile dermatomyositis. Int J Clin Rheumtol 2012;7:325–33. 10.2217/ijr.12.23 - DOI
    1. Orandi AB, Baszis KW, Dharnidharka VR, et al. . Assessment, classification and treatment of calcinosis as a complication of juvenile dermatomyositis: a survey of pediatric rheumatologists by the childhood arthritis and rheumatology research alliance (CARRA). Pediatr Rheumatol 2017;15:71. 10.1186/s12969-017-0199-4 - DOI - PMC - PubMed
    1. Al Muderis M, Azzopardi T, Cundy P. Zebra lines of pamidronate therapy in children. J Bone Joint Surg Am 2007;89:1511–6. 10.2106/00004623-200707000-00015 - DOI - PubMed

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