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Case Reports
. 2022:30:e01628.
doi: 10.1016/j.idcr.2022.e01628. Epub 2022 Nov 1.

Monkeypox associated myocarditis: A case report

Philippe Brouillard  1   2 , Anthony Valin-Thorburn  1   2 , Yves Provost  1   3 , Arpita Chakravarti  1   4 , George Honos  1   2 , François Tournoux  1   2   5 , Cécile Tremblay  1   4   5
Affiliations
Case Reports

Monkeypox associated myocarditis: A case report

Philippe Brouillard et al. IDCases. 2022.

Abstract

Monkeypox is a zoonotic Orthopoxvirus infection usually present in regions of Africa. Recent outbreaks of Monkeypox infection have been reported in non endemic region and human-to-human contact is believed to be the main driver for propagation. While the disease is usually self-contained, severe complications, such as neurological and ocular involvements may arise. We report the case of a 34-year-old male who presented with myocarditis and concurrent genital Monkeypox infection. Other usual causes of myocardial injury were ruled out. We believe it to be the first documented case of myocarditis secondary to Monkeypox. We report a new complication of the disease and the possible underlying mechanisms. Our case report raises awareness about possible unknown complications of Monkeypox as outbreaks continue to happen around the world.

Keywords: Monkeypox; Myocarditis.

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Conflict of interest statement

The authors report no declarations of interest.

Figures

Fig. 1
Fig. 1
ECG on arrival. Antero-lateral concave ST elevation compatible with pericarditis.
Fig. 2
Fig. 2
Trans-thoracic Echocardiogram performed the day after the presentation. Diffuse mild left ventricular systolic dysfunction, more important at the apex. Left ventricular ejection fraction is measured at 44 %.
Fig. 3
Fig. 3
Cardiac MRI confirmed the mildly reduced ejection fraction. It demonstrated also a limited late gadolinium enhancement at the apex (left) as well as high T2 and extracellular volume values compatible with edema and injury of the myocardium (middle and right). No pericardial involvement was reported.
See this image and copyright information in PMC

References

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    1. Prevention Centers for Disease Control and. Case identified after monkeypox clusters in several other countries; 2022. 〈https://www.cdc.gov/media/releases/2022/s0518-monkeypox-case.html〉.

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