CD40LG Triplication Associates with Immune Dysregulation and Exhaustion
- PMID: 36346498
- DOI: 10.1007/s10875-022-01392-5
CD40LG Triplication Associates with Immune Dysregulation and Exhaustion
Comment on
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Hematopoietic Stem Cell Transplantation Successfully Treats CD40LG Duplication.J Clin Immunol. 2021 Oct;41(7):1668-1670. doi: 10.1007/s10875-021-01085-5. Epub 2021 Jun 22. J Clin Immunol. 2021. PMID: 34159508 No abstract available.
References
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- Mehling A, Loser K, Varga G, Metze D, Luger TA, Schwarz T et al (2001) Overexpression of Cd40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity. J Exp Med 615–28. https://doi.org/10.1084/jem.194.5.615
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- Sun D, Le Coz C, Bunin N, Romberg N (2021) Hematopoietic stem cell transplantation successfully treats CD40LG duplication. J Clin Immunol 1668–70. https://doi.org/10.1007/s10875-021-01085-5
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- Le Coz C, Trofa M, Syrett CM, Martin A, Jyonouchi H, Jyonouchi S, et al. CD40LG duplication-associated autoimmune disease is silenced by nonrandom X-chromosome inactivation. J Allergy Clin Immunol. 2018;141:2308-11.e7. - DOI
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