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Case Reports
. 2022 Oct 5;14(10):e29948.
doi: 10.7759/cureus.29948. eCollection 2022 Oct.

Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report

Sarvani Reddy Allam  1 , Mridula Sree Naagendran  2 , Jaison Lawrence Alexander Santhi  3 , Ratesh Khillan  4
Affiliations
Case Reports

Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report

Sarvani Reddy Allam et al. Cureus. .

Abstract

Synchronous dual haematological neoplasms are always challenging in both diagnosis and treatment. Here, we report the case of a 73-year-old African American female patient with the coexistence of post-essential thrombocythemia myelofibrosis with MPL positive mutation and monoclonal gammopathy of undetermined significance (MGUS). Our management plan focuses on her anaemia and regular monitoring for observing MGUS transforming into an aggressive multiple myeloma.

Keywords: bone marrow; hematology-oncology; mgus; myelofibrosis; thrombocythemia.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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