Invasive Techniques in Scar Management: Fat Injections
- PMID: 36351151
- Bookshelf ID: NBK586117
- DOI: 10.1007/978-3-030-44766-3_39
Invasive Techniques in Scar Management: Fat Injections
Excerpt
Since the end of the nineteenth century, fat grafting has become one of the most promising treatments for posttraumatic deformities and more in general for scars. Its easy application and collection have made it as the ideal therapy to restore volume and pliability, and contour and to prevent symptoms as pain. In these years the application method, the indications and the guidelines have been changed many times. In this chapter, we analyze why fat grafting is becoming so popular in the twentieth century and what is the scientific rational to use autologous adipose tissue. We will also discuss the current guidelines and the possible applications. At the end, we will also present some new fields such as the application of autologous fat grafting in the treatment of the hypertrophic scars and how we can try to improve its engraftment using external mechanical forces (the external negative pressure therapy) and/or the plasma-rich platelet (PRP).
Copyright 2020, The Author(s).
Sections
- 39.1. Adipose-Derived Stem Cells: Their Biological Properties
- 39.2. The Guidelines
- 39.3. The Procedure
- 39.4. The Free Fat Grafting and Scars [–9] (◘ Figs. 39.5, 39.6, 39.7, and 39.8)
- 39.5. The Ancillary Procedures to Increase the Overall Survival of Adipose Cells
- 39.6. Something to Discuss: The Oncological Point of View
- 39.7. Conclusion
- References
References
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- US Department of Health and Human Services. Tissue guidances: human cells, tissues, and cellular and tissue-based products (hct/ps) from adipose tissue: regulatory considerations; draft guidance. www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformati.... Accessed 8 June 2015.
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- American Society of Plastic Surgeons and the Plastic Surgery Foundation. Docket #FDA-2014-D-1856 (HCT/Ps). www.plasticsurgery.org/Documents/Legislation-Advocacy/Regulatory/asps-re.... Accessed 7 July 2015.
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- Bassetto F, et al. Adipose-derived stem cells to modulate scar tissue: from biological basis to clinical application. In: Shiffman MA, Di Giuseppe A, editors. Stem cells in aesthetic procedures. art, science and clinical techniques. Berlin: Springer; 2014.
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- Bassetto F, et al. Fat grafting in the treatment of skin fibrosis and scars. J Wound Technol. 2014;24:17–19.
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- Mojallal A, et al. Improvement of skin quality after fat grafting: clinical and observation and an animal study. Plast Reconstr Surg. 2009;124:765. - PubMed
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