Laying the foundation for single-cell studies in bats

Arinjay Banerjee¹, Karen Mossman²

Affiliations

¹ Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: arinjay.banerjee@usask.ca.
² Institute for Infectious Disease Research, McMaster University, Hamilton, ON L8S 4K1, Canada; McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada. Electronic address: mossk@mcmaster.ca.

PMID: 36351371
DOI: 10.1016/j.immuni.2022.10.010

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Laying the foundation for single-cell studies in bats

Arinjay Banerjee et al. Immunity. 2022.

Free article

. 2022 Nov 8;55(11):1974-1977.

doi: 10.1016/j.immuni.2022.10.010.

Authors

Arinjay Banerjee¹, Karen Mossman²

Affiliations

¹ Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: arinjay.banerjee@usask.ca.
² Institute for Infectious Disease Research, McMaster University, Hamilton, ON L8S 4K1, Canada; McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada. Electronic address: mossk@mcmaster.ca.

PMID: 36351371
DOI: 10.1016/j.immuni.2022.10.010

Abstract

Bats serve as hosts of viruses that can cause disease in humans. In this issue of Immunity, Gamage et al. characterize the immune cell repertoire in Eonycteris spelaea bat lung tissue using single-cell transcriptomics, providing insight into the in vivo immune response to infection with a Pteropine orthoreovirus (PRV3M) and establishing a paradigm for future comparative immunology studies.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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Single-cell transcriptome analysis of the in vivo response to viral infection in the cave nectar bat Eonycteris spelaea.
Gamage AM, Chan WOY, Zhu F, Lim YT, Long S, Ahn M, Tan CW, Hiang Foo RJ, Sia WR, Lim XF, He H, Zhai W, Anderson DE, Sobota RM, Dutertre CA, Wang LF. Gamage AM, et al. Immunity. 2022 Nov 8;55(11):2187-2205.e5. doi: 10.1016/j.immuni.2022.10.008. Immunity. 2022. PMID: 36351376

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Laying the foundation for single-cell studies in bats

Affiliations

Laying the foundation for single-cell studies in bats

Authors

Affiliations

Abstract

Conflict of interest statement

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MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources