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. 2022 Dec 15;11(12):e0080222.
doi: 10.1128/mra.00802-22. Epub 2022 Nov 10.

Coding-Complete Genome Sequences for Two Confirmed Monkeypox Cases in South Africa 2022

Wai Yin Chan  1   2 , Phillip Senzo Mtshali  1 , Antoinette Grobbelaar  1 , Naazneen Moolla  1   3 , Thabo Mohale  1 , Michelle Lowe  1 , Morne Du Plessis  1 , Arshad Ismail  1   4 , Jacqueline Weyer  1   3   5
Affiliations

Coding-Complete Genome Sequences for Two Confirmed Monkeypox Cases in South Africa 2022

Wai Yin Chan et al. Microbiol Resour Announc. .

Abstract

The coding-complete genome sequences of monkeypox virus (MPXV) were obtained from skin lesion swabs from two human cases detected in South Africa in June 2022. Sequence analyses indicated that the genetic sequences of the viruses associated with these two cases were related most closely to the genetic sequences of other MPXVs reported during the 2022 multicountry outbreak and belong to the monkeypox hMPXV-1 clade (previously West Africa clade) and B.1 lineage.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIG 1
FIG 1
Maximum likelihood tree of the hMPXV-1 clade. Both NICD-SVPL223 and SVPL232 grouped in the hMPXV-1 clade, B.1 lineage. Alignment of the MPXV genomes and the consensus sequences of NICD-SVPL223 and NICD-SVPL232 were generated using MAFFT v7.505 (16) and were curated. The phylogenetics tree was constructed using IQ-TREE2 v2.0.3 (17) using the best-fit model from ModelFinder and a 1,000 ultrafast bootstrap.
See this image and copyright information in PMC

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