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Review
. 2022 Oct 26;8(11):1126.
doi: 10.3390/jof8111126.

Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia

Affiliations
Review

Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia

Nishanthinie Thatchanamoorthy et al. J Fungi (Basel). .

Abstract

Candida auris, a newly emerging healthcare-associated yeast pathogen from the Metschnikowiaceae family, was first described in the ear canal of an elderly Japanese patient in 2009. The yeast is one of the causative agents of candidemia, which has been linked with nosocomial outbreaks and high mortality rates in healthcare facilities worldwide. Since its first isolation, the occurrence of C. auris in six continents has becomes a grave concern for the healthcare professionals and scientific community. Recent reports showed the identification of five geographically distinct clades and high rates of antifungal resistance associated with C. auris. Till date, there are no effective treatment options, and standardized measures for prevention and control of C. auris infection in healthcare facilities. This leads to frequent therapeutic failures and complicates the eradication of C. auris infection in healthcare facilities. Thus, this review focuses on the recent understanding of the epidemiology, risk factors, diagnosis, transmission and prevention and control strategies of C. auris infection in healthcare facilities in Asia.

Keywords: Candida auris; epidemiology; invasive fungal infections.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Spivak E.S., Hanson K.E. Candida auris: An Emerging Fungal Pathogen. J. Clin. Microbiol. 2018;56:e01588-17. doi: 10.1128/JCM.01588-17. - DOI - PMC - PubMed
    1. Calvo B., Melo A.S., Perozo-Mena A., Hernandez M., Francisco E.C., Hagen F., Meis J.F., Colombo A.L. First report of Candida auris in America: Clinical and microbiological aspects of 18 episodes of candidemia. J. Infect. 2016;73:369–374. doi: 10.1016/j.jinf.2016.07.008. - DOI - PubMed
    1. Rossato L., Colombo A.L. Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity? Front. Microbiol. 2018;9:3081. doi: 10.3389/fmicb.2018.03081. - DOI - PMC - PubMed
    1. Piedrahita C.T., Cadnum J.L., Jencson A.L., Shaikh A.A., Ghannoum M.A., Donskey C.J. Environmental Surfaces in Healthcare Facilities are a Potential Source for Transmission of Candida auris and Other Candida Species. Infect. Control. Hosp. Epidemiol. 2017;38:1107–1109. doi: 10.1017/ice.2017.127. - DOI - PubMed
    1. Fu L., Le T., Liu Z., Wang L., Guo H., Yang J., Chen Q., Hu J. Different efficacies of common disinfection methods against Candida auris and other Candida species. J. Infect. Public Health. 2020;13:730–736. doi: 10.1016/j.jiph.2020.01.008. - DOI - PubMed

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