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. 2023:277:73-116.
doi: 10.1007/164_2022_616.

Metabolomics and NMR

Ryan T McKay  1
Affiliations

Metabolomics and NMR

Ryan T McKay. Handb Exp Pharmacol. 2023.

Abstract

The purpose of this manuscript will be to convince the reader to dive deeper into NMR spectroscopy and prevent the technique from being just another "black-box" in the lab. We will try to concisely highlight interesting topics and supply additional references for further exploration at each stage. The advantages of delving into the technique will be shown. The secondary objective, i.e., avoiding common problems before starting, will hopefully then become clear. Lastly, we will emphasize the spectrometer information needed for manuscript reporting to allow reproduction of results and confirm findings.

Keywords: Automation; Biochemistry; Liquids; Metabolites; Metabolomics; NMR; Nuclear magnetic resonance; Quantitation; Small molecule; Solvent suppression; Spectrometry.

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