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Review
. 2022 Dec:227:107211.
doi: 10.1016/j.cmpb.2022.107211. Epub 2022 Oct 31.

Review of research on the instance segmentation of cell images

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Review

Review of research on the instance segmentation of cell images

Tingxi Wen et al. Comput Methods Programs Biomed. 2022 Dec.

Abstract

The instance segmentation of cell images is the basis for conducting cell research and is of great importance for the study and diagnosis of pathologies. To analyze current situations and future developments in the field of cell image instance segmentation, this paper first systematically reviews image segmentation methods based on traditional and deep learning methods. Then, from the three aspects of cell image weak label extraction, cell image instance segmentation, and cell internal structure segmentation, deep-learning-based cell image segmentation methods are analyzed and summarized. Finally, cell image instance segmentation is summarized, and challenges and future developments are discussed.

Keywords: Cell segmentation; Deep learning; Target detection.

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Conflict of interest statement

Declaration of Competing Interest No conflict of interest exits in the submission of this manuscript, and manuscript is approved by all authors for publication. I would like to declare on behalf of my co-authors that the work described was original research that has not been published previously, and not under consideration for publication elsewhere, in whole or in part. All the authors listed have approved the manuscript that is enclosed.

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