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. 2022 Nov 10;80(1):231.
doi: 10.1186/s13690-022-00983-3.

COVID-19 and aerobic exercise: possible role of angiotensin converting enzyme 2

Haidar Djemai #  1   2 , Rami Hammad #  3 , Ibrahim M Dabayebeh  4 , Saleh Hammad  5 , Abdellah Merzouk  6 , Xavier Coumoul  7 , Philippe Noirez  8   7   3   9
Affiliations

COVID-19 and aerobic exercise: possible role of angiotensin converting enzyme 2

Haidar Djemai et al. Arch Public Health. .

Abstract

The emergence and circulation of a novel coronavirus (2019-nCoV)-Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-set off a global health crisis. SARS-CoV-2 spreads faster than its two ancestors, SARS-CoV and MERS-CoV. Several modes of transmission have been identified: via respiratory droplets, contact with infected people or contaminated surfaces, and potentially, bioaerosols. Various countries have taken preventive measures that may include partial or total lockdowns lasting weeks. The physical inactivity associated with lockdowns may promote cardiometabolic or other diseases, while physical activity may play a critical role in preventing them. Here we develop the hypothesis of the involvement of aerosols in the contamination process, the role of angiotensin converting enzyme 2 (ACE2), the potential benefits and harm of physical activity during lockdowns, and we suggest directions for future research.

Keywords: COVID-19; Outdoor exercise; Physical activity; SARS-CoV-2.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Possible mechanism of contamination by SARS-CoV-2 during endurance exercise within urban environment in presence of pollutants or bioaerosols. ACE2: angiotensin converting enzyme 2; PM2.5: fine particles (particulate matter) of diameter ≤ 2.5 μm
See this image and copyright information in PMC

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