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. 2022 Nov 9;11(11):1581.
doi: 10.3390/antibiotics11111581.

Evolution of the Concept of Sepsis

Jean-Louis Vincent  1
Affiliations

Evolution of the Concept of Sepsis

Jean-Louis Vincent. Antibiotics (Basel). .

Abstract

Sepsis has been recognized for more than 2500 years, but the criteria used to identify it have evolved. Sepsis is an infection associated with some degree of organ dysfunction-put very simplistically, sepsis is a 'bad infection'. Specific criteria may be useful for research purposes but have less value in day-to-day clinical practice. What is relevant here is early recognition and some awareness of severity so that appropriate therapy can be started without delay.

Keywords: definition; infection; inflammation; organ dysfunction.

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Conflict of interest statement

The author declares no conflict of interest.

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