Fighting Cancer around the World: A Framework for Action

Denis Horgan^{1

2}, Rizwana Mia³, Tosan Erhabor⁴, Yosr Hamdi^{5

6}, Collet Dandara⁷, Jonathan A Lal^{2

8}, Joel Fokom Domgue^{9

10}, Oladimeji Ewumi¹¹, Teresia Nyawira¹², Salomé Meyer¹³, Dominique Kondji¹⁴, Ngiambudulu M Francisco¹⁵, Sadakatsu Ikeda¹⁶, Chai Chuah¹⁷, Roselle De Guzman¹⁸, Anupriya Paul¹⁹, Krishna Reddy Nallamalla²⁰, Woong-Yang Park²¹, Vijay Tripathi², Ravikant Tripathi²², Amber Johns²³, Mohan P Singh²⁴, Maude E Phipps²⁵, France Dube²⁶, Kate Whittaker²⁷, Deborah Mukherji^{28

29}, Hadi Mohamad Abu Rasheed³⁰, Marta Kozaric¹, Joseph A Pinto³¹, Stephen Doral Stefani³², Federico Augustovski³³, Maria Eugenia Aponte Rueda³⁴, Ricardo Fujita Alarcon³⁵, Hugo A Barrera-Saldana^{36

37}

Affiliations

¹ European Alliance for Personalised Medicine, 1040 Brussels, Belgium.
² Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, India.
³ Genomics Centre, South African Medical Research Council, Tygerberg, Cape Town 7500, South Africa.
⁴ Medical Laboratory Science Council of Nigeria (MLSCN), Durumi, Abuja 900110, Nigeria.
⁵ Laboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
⁶ Laboratory of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis 1002, Tunisia.
⁷ Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Observatory, Cape Town 7925, South Africa.
⁸ Institute for Public Health Genomics, Department of Genetics and Cell Biology, GROW School of Oncology and Developmental Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands.
⁹ Departments of Epidemiology, and Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Centre, Houston, TX 77030, USA.
¹⁰ Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaounde, Yaounde VF7W+4M9, Cameroon.
¹¹ Freelance Health Care, Life Sciences, Medical Artificial Intelligence Content Writer, Lagos 100253, Nigeria.
¹² National Commission for Science, Technology and Innovation in Kenya (NACOSTI), Nairobi 00100, Kenya.
¹³ Cancer Alliance, Cape Town 7700, South Africa.
¹⁴ Health & Development Communication, Building Capacities for Better Health in Africa, Yaounde P.O. Box 2032, Cameroon.
¹⁵ Grupo de Investigação Microbiana e Imunológica, Instituto Nacional de Investigação em Saúde (National Institute for Health Research), Luanda 3635, Angola.
¹⁶ Department of Precision Cancer Medicine, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
¹⁷ Singularity University, P.O. Box 165, Gold Coast, QLD 4227, Australia.
¹⁸ Oncology and Pain Management Section, Manila Central University-Filemon D. Tanchoco Medical Foundation Hospital, Caloocan 1400, Philippines.
¹⁹ Department of Mathematics and Statistics, Faculty of Science, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, India.
²⁰ ACCESS Health India, Hyderabad 500086, India.
²¹ Samsung Genome Institute, Samsung Medical Centre, Sungkyunkwan University, Seoul 06351, Korea.
²² Ministry of Labor, Health Department Government of India, New Delhi 110001, India.
²³ Garvan Institute of Medical Research and the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.
²⁴ Centre of Biotechnology, University of Allahabad, Allahabad 211002, India.
²⁵ Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya 47500, Selangor, Malaysia.
²⁶ Astra Zeneca, 1800 Concord Pike, Wilmington, DE 19803, USA.
²⁷ Cancer Council Australia, Sydney, NSW 2000, Australia.
²⁸ Global Health Institute, American University of Beirut, Beirut VFXP+7QF, Lebanon.
²⁹ Department of Hematology/Oncology, American University of Beirut Medical Centre, Beirut P.O. Box 11-0236, Lebanon.
³⁰ Qatar Cancer Society, Doha 22944, Qatar.
³¹ Centre for Basic and Translational Research, Auna Ideas, Lima 15036, Peru.
³² UNIMED RS, Porto Alegre 90040-180, Brazil.
³³ Health Technology Assessment and Health Economics, Department of the Institute for Clinical Effectiveness and Health Policy (IECS-CONICET), Buenos Aires C1056ABH, Argentina.
³⁴ Venezuelan Breast Cancer Research and Education Foundation, Caracas 1060, Venezuela.
³⁵ Centro de Genética y Biología Molecular, Universidad de San Martín de Porres, Lima 15024, Peru.
³⁶ Innbiogem SC/Vitagenesis SA at National Laboratory for Services of Research, Development, and Innovation for the Pharma and Biotech Industries (LANSEIDI) of CONACyT Vitaxentrum Group, Monterrey 64630, Mexico.
³⁷ Schools of Medicine and Biology, Autonomous University of Nuevo Leon, Monterrey 66451, Mexico.

PMID: 36360466
PMCID: PMC9690702
DOI: 10.3390/healthcare10112125

Fighting Cancer around the World: A Framework for Action

Denis Horgan et al. Healthcare (Basel). 2022.

. 2022 Oct 25;10(11):2125.

doi: 10.3390/healthcare10112125.

Authors

Affiliations

¹ European Alliance for Personalised Medicine, 1040 Brussels, Belgium.
² Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, India.
³ Genomics Centre, South African Medical Research Council, Tygerberg, Cape Town 7500, South Africa.
⁴ Medical Laboratory Science Council of Nigeria (MLSCN), Durumi, Abuja 900110, Nigeria.
⁵ Laboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
⁶ Laboratory of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis 1002, Tunisia.
⁷ Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Observatory, Cape Town 7925, South Africa.
⁸ Institute for Public Health Genomics, Department of Genetics and Cell Biology, GROW School of Oncology and Developmental Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands.
⁹ Departments of Epidemiology, and Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Centre, Houston, TX 77030, USA.
¹⁰ Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaounde, Yaounde VF7W+4M9, Cameroon.
¹¹ Freelance Health Care, Life Sciences, Medical Artificial Intelligence Content Writer, Lagos 100253, Nigeria.
¹² National Commission for Science, Technology and Innovation in Kenya (NACOSTI), Nairobi 00100, Kenya.
¹³ Cancer Alliance, Cape Town 7700, South Africa.
¹⁴ Health & Development Communication, Building Capacities for Better Health in Africa, Yaounde P.O. Box 2032, Cameroon.
¹⁵ Grupo de Investigação Microbiana e Imunológica, Instituto Nacional de Investigação em Saúde (National Institute for Health Research), Luanda 3635, Angola.
¹⁶ Department of Precision Cancer Medicine, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
¹⁷ Singularity University, P.O. Box 165, Gold Coast, QLD 4227, Australia.
¹⁸ Oncology and Pain Management Section, Manila Central University-Filemon D. Tanchoco Medical Foundation Hospital, Caloocan 1400, Philippines.
¹⁹ Department of Mathematics and Statistics, Faculty of Science, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, India.
²⁰ ACCESS Health India, Hyderabad 500086, India.
²¹ Samsung Genome Institute, Samsung Medical Centre, Sungkyunkwan University, Seoul 06351, Korea.
²² Ministry of Labor, Health Department Government of India, New Delhi 110001, India.
²³ Garvan Institute of Medical Research and the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.
²⁴ Centre of Biotechnology, University of Allahabad, Allahabad 211002, India.
²⁵ Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya 47500, Selangor, Malaysia.
²⁶ Astra Zeneca, 1800 Concord Pike, Wilmington, DE 19803, USA.
²⁷ Cancer Council Australia, Sydney, NSW 2000, Australia.
²⁸ Global Health Institute, American University of Beirut, Beirut VFXP+7QF, Lebanon.
²⁹ Department of Hematology/Oncology, American University of Beirut Medical Centre, Beirut P.O. Box 11-0236, Lebanon.
³⁰ Qatar Cancer Society, Doha 22944, Qatar.
³¹ Centre for Basic and Translational Research, Auna Ideas, Lima 15036, Peru.
³² UNIMED RS, Porto Alegre 90040-180, Brazil.
³³ Health Technology Assessment and Health Economics, Department of the Institute for Clinical Effectiveness and Health Policy (IECS-CONICET), Buenos Aires C1056ABH, Argentina.
³⁴ Venezuelan Breast Cancer Research and Education Foundation, Caracas 1060, Venezuela.
³⁵ Centro de Genética y Biología Molecular, Universidad de San Martín de Porres, Lima 15024, Peru.
³⁶ Innbiogem SC/Vitagenesis SA at National Laboratory for Services of Research, Development, and Innovation for the Pharma and Biotech Industries (LANSEIDI) of CONACyT Vitaxentrum Group, Monterrey 64630, Mexico.
³⁷ Schools of Medicine and Biology, Autonomous University of Nuevo Leon, Monterrey 66451, Mexico.

PMID: 36360466
PMCID: PMC9690702
DOI: 10.3390/healthcare10112125

Abstract

Tackling cancer is a major challenge right on the global level. Europe is only the tip of an iceberg of cancer around the world. Prosperous developed countries share the same problems besetting Europe-and the countries and regions with fewer resources and less propitious conditions are in many cases struggling often heroically against a growing tide of disease. This paper offers a view on these geographically wider, but essentially similar, challenges, and on the prospects for and barriers to better results in this ceaseless battle. A series of panels have been organized by the European Alliance for Personalised Medicine (EAPM) to identify different aspects of cancer care around the globe. There is significant diversity in key issues such as NGS, RWE, molecular diagnostics, and reimbursement in different regions. In all, it leads to disparities in access and diagnostics, patients' engagement, and efforts for a better understanding of cancer.

Keywords: cancer; diagnostics; genomics; global; health care; liquid biopsy; next-generation sequencing; patients; personalized medicine; policy framework; reimbursement.

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Conflict of interest statement

D.H. and M.K. are employees of the European Alliance for Personalised Medicine, which receives funding from both the public and private sectors. France Dube is an employee of Astra Zeneca. Amber Johns is a consultant to the ICGC ARGO project.

Figures

**Figure 1**
Research strategy applied. Methodology used to provide policy framework for tackling cancer on the global level.

See this image and copyright information in PMC

References

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Fighting Cancer around the World: A Framework for Action

Affiliations

Fighting Cancer around the World: A Framework for Action

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

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