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. 2022 Nov 7;27(21):7632.
doi: 10.3390/molecules27217632.

Flavonoids from Sedum japonicum subsp. oryzifolium (Crassulaceae)

Takayuki Mizuno  1 , Nahoko Uchiyama  2 , Seiji Tanaka  2 , Takahisa Nakane  3 , Hari Prasad Devkota  4 , Kazumi Fujikawa  5 , Nobuo Kawahara  5 , Tsukasa Iwashina  1
Affiliations

Flavonoids from Sedum japonicum subsp. oryzifolium (Crassulaceae)

Takayuki Mizuno et al. Molecules. .

Abstract

Twenty-two flavonoids were isolated from the leaves and stems of Sedum japonicum subsp. oryzifolium (Crassulaceae). Of these compounds, five flavonoids were reported in nature for the first time, and identified as herbacetin 3-O-xyloside-8-O-glucoside, herbacetin 3-O-glucoside-8-O-(2'''-acetylxyloside), gossypetin 3-O-glucoside-8-O-arabinoside, gossypetin 3-O-glucoside-8-O-(2'''-acetylxyloside) and hibiscetin 3-O-glucoside-8-O-arabinoside via UV, HR-MS, LC-MS, acid hydrolysis and NMR. Other seventeen known flavonoids were identified as herbacetin 3-O-glucoside-8-O-arabinoside, herbacetin 3-O-glucoside-8-O-xyloside, gossypetin 3-O-glucoside-8-O-xyloside, quercetin, quercetin 3-O-glucoside, quercetin 3-O-xylosyl-(1→2)-rhamnoside-7-O-rhamnoside, quercetin 3-O-rhamnoside-7-O-glucoside, kaempferol, kaempferol 3-O-glucoside, kaempferol 7-O-rhamnoside, kaempferol 3,7-di-O-rhamnoside, kaempferol 3-O-glucoside-7-O-rhamnoside, kaempferol 3-O-glucosyl-(1→2)-rhamnoside-7-O-rhamnoside, kaempferol 3-O-xylosyl-(1→2)-rhamnoside, kaempferol 3-O-xylosyl-(1→2)-rhamnoside-7-O-rhamnoside, myricetin 3-O-glucoside and cyanidin 3-O-glucoside. Some flavonol 3,8-di-O-glycosides were found in Sedum japonicum subsp. oryzifolium as major flavonoids in this survey. They were presumed to be the diagnostic flavonoids in the species. Flavonoids were reported from S. japonicum for the first time.

Keywords: NMR; Sedum japonicum subsp. oryzifolium; flavonol 3,8-di-O-glycosides; gossypetin; herbacetin; hibiscetin.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chemical structures of flavonoids from Sedum japonicum subsp. oryzifolium.
See this image and copyright information in PMC

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