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Review
. 2022 Dec 1;35(6):718-727.
doi: 10.1097/WCO.0000000000001116.

Traumatic peripheral nerve injuries: diagnosis and management

Stephanie L Barnes  1   2   3 , Thomas A Miller  4 , Neil G Simon  5
Affiliations
Review

Traumatic peripheral nerve injuries: diagnosis and management

Stephanie L Barnes et al. Curr Opin Neurol. .

Abstract

Purpose of review: To review advances in the diagnostic evaluation and management of traumatic peripheral nerve injuries.

Recent findings: Serial multimodal assessment of peripheral nerve injuries facilitates assessment of spontaneous axonal regeneration and selection of appropriate patients for early surgical intervention. Novel surgical and rehabilitative approaches have been developed to complement established strategies, particularly in the area of nerve grafting, targeted rehabilitation strategies and interventions to promote nerve regeneration. However, several management challenges remain, including incomplete reinnervation, traumatic neuroma development, maladaptive central remodeling and management of fatigue, which compromise functional recovery.

Summary: Innovative approaches to the assessment and treatment of peripheral nerve injuries hold promise in improving the degree of functional recovery; however, this remains a complex and evolving area.

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References

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    1. Stoll G, Jander S, Myers RR. Degeneration and regeneration of the peripheral nervous system: from Augustus Waller's Observations to neuroinflammation. J Peripher Nerv Syst 2002; 7:13–27.

MeSH terms