Mouse Corneal Transplantation

doi:10.1007/978-1-0716-2835-5_3

. 2023:2597:19-24.

doi: 10.1007/978-1-0716-2835-5_3.

Mouse Corneal Transplantation

Peng Chen¹, Ki Ho Park¹, Liqiang Zhang², Alexandra R Lucas², Heather L Chandler³, Hua Zhu⁴

Affiliations

¹ Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
² Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ, USA.
³ College of Optometry, The Ohio State University, Columbus, OH, USA. Chandler.111@osu.edu.
⁴ Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Hua.Zhu@osumc.edu.

PMID: 36374411
DOI: 10.1007/978-1-0716-2835-5_3

Mouse Corneal Transplantation

Peng Chen et al. Methods Mol Biol. 2023.

. 2023:2597:19-24.

doi: 10.1007/978-1-0716-2835-5_3.

Authors

Peng Chen¹, Ki Ho Park¹, Liqiang Zhang², Alexandra R Lucas², Heather L Chandler³, Hua Zhu⁴

Affiliations

¹ Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
² Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ, USA.
³ College of Optometry, The Ohio State University, Columbus, OH, USA. Chandler.111@osu.edu.
⁴ Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Hua.Zhu@osumc.edu.

PMID: 36374411
DOI: 10.1007/978-1-0716-2835-5_3

Abstract

Corneal transplantation is the most common form of organ transplantation worldwide. Transplant survival depends on various factors, many of which are not fully understood. Due to the existence of many genetically defined strains, mouse models of corneal transplantation are most commonly used. Here, we describe a method for a mouse corneal transplantation.

Keywords: Corneal transplant; Inflammation; Mouse; Vascularized.

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Cited by

Neutrophil pyroptosis regulates corneal wound healing and post-injury neovascularisation.
Chen P, Zhang Z, Sakai L, Xu Y, Wang S, Lee KE, Geng B, Kim J, Zhao B, Wang Q, Wen H, Chandler HL, Zhu H. Chen P, et al. Clin Transl Med. 2024 Nov;14(11):e1762. doi: 10.1002/ctm2.1762. Clin Transl Med. 2024. PMID: 39496510 Free PMC article.

References

1. Hancox Z, Heidari Keshel S, Yousaf S, Saeinasab M, Shahbazi MA, Sefat F (2020) The progress in corneal translational medicine. Biomater Sci 8(23):6469–6504 - DOI - PubMed
1. Ambati BK, Nozaki M, Singh N et al (2006) Corneal avascularity is due to soluble VEGF receptor-1. Nature 443(7114):993–997 - DOI - PubMed - PMC
1. Tan DT, Dart JK, Holland EJ, Kinoshita SJTL (2012) Corneal transplantation. 379(9827):1749–1761
1. Bock F, Maruyama K, Regenfuss B et al (2013) Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases. Prog Retin Eye Res 34:89–124 - DOI - PubMed
1. Sekiyama E, Nakamura T, Cooper LJ et al (2006) Unique distribution of thrombospondin-1 in human ocular surface epithelium. Invest Ophthalmol Vis Sci 47(4):1352–1358 - DOI - PubMed

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[1] Hancox Z, Heidari Keshel S, Yousaf S, Saeinasab M, Shahbazi MA, Sefat F (2020) The progress in corneal translational medicine. Biomater Sci 8(23):6469–6504 - DOI - PubMed

[2] Hancox Z, Heidari Keshel S, Yousaf S, Saeinasab M, Shahbazi MA, Sefat F (2020) The progress in corneal translational medicine. Biomater Sci 8(23):6469–6504 - DOI - PubMed

[3] Ambati BK, Nozaki M, Singh N et al (2006) Corneal avascularity is due to soluble VEGF receptor-1. Nature 443(7114):993–997 - DOI - PubMed - PMC

[4] Ambati BK, Nozaki M, Singh N et al (2006) Corneal avascularity is due to soluble VEGF receptor-1. Nature 443(7114):993–997 - DOI - PubMed - PMC

[5] Tan DT, Dart JK, Holland EJ, Kinoshita SJTL (2012) Corneal transplantation. 379(9827):1749–1761

[6] Tan DT, Dart JK, Holland EJ, Kinoshita SJTL (2012) Corneal transplantation. 379(9827):1749–1761

[7] Bock F, Maruyama K, Regenfuss B et al (2013) Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases. Prog Retin Eye Res 34:89–124 - DOI - PubMed

[8] Bock F, Maruyama K, Regenfuss B et al (2013) Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases. Prog Retin Eye Res 34:89–124 - DOI - PubMed

[9] Sekiyama E, Nakamura T, Cooper LJ et al (2006) Unique distribution of thrombospondin-1 in human ocular surface epithelium. Invest Ophthalmol Vis Sci 47(4):1352–1358 - DOI - PubMed

[10] Sekiyama E, Nakamura T, Cooper LJ et al (2006) Unique distribution of thrombospondin-1 in human ocular surface epithelium. Invest Ophthalmol Vis Sci 47(4):1352–1358 - DOI - PubMed

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Mouse Corneal Transplantation

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