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. 2023 Feb 1;80(2):121-122.
doi: 10.1001/jamaneurol.2022.3978.

The Future of Functional Neuroimaging in Parkinsonism: Prove It!

Scott A Norris  1   2 , Joel S Perlmutter  1   2
Affiliations

The Future of Functional Neuroimaging in Parkinsonism: Prove It!

Scott A Norris et al. JAMA Neurol. .
No abstract available

Plain language summary

This Viewpoint discusses the current lack of evidence of functional neuroimaging affecting patient outcomes in parkinsonian conditions.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Norris reported grants from the National Institutes of Health for research, Dystonia Medical Research Foundation, and National Spasmodic Dysphonia Association and has a patent pending for 17/116,712 at Washington University. Dr Perlmutter reported grants from the National Institutes of Health, Barnes Jewish Hospital Foundation, American Parkinson Disease Association, Huntington Disease Society of America, and Paula and Rodger Riney Fund. No other disclosures were reported.

References

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    1. Perlmutter JS, Norris SA. Neuroimaging biomarkers for Parkinson disease: facts and fantasy. Ann Neurol. 2014;76(6):769–783. doi: 10.1002/ana.24291 - DOI - PMC - PubMed
    1. Bega D, Kuo PH, Chalkidou A, et al. Clinical utility of DaTscan in patients with suspected Parkinsonian syndrome: a systematic review and meta-analysis. NPJ Parkinsons Dis. 2021;7(1):43. doi: 10.1038/s41531-021-00185-8 - DOI - PMC - PubMed
    1. Lo B, Field MJ; Institute of Medicine (US) Committee on Conflict of Interest in Medical Research, Education, and Practice. Conflict of Interest in Medical Research, Education, and Practice. National Academies Press; 2009. - PubMed
    1. Mitchell T, Lehéricy S, Chiu SY, Strafella AP, Stoessl AJ, Vaillancourt DE. Emerging neuroimaging biomarkers across disease stage in Parkinson disease: a review. JAMA Neurol. 2021;78(10):1262–1272. doi: 10.1001/jamaneurol.2021.1312 - DOI - PMC - PubMed

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