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Review
. 2022 Dec;26(8):e14398.
doi: 10.1111/petr.14398.

Clinical approach to antibody-mediated rejection from the pediatric heart transplant society

Shahnawaz Amdani  1 , Heather Henderson  2 , Melanie D Everitt  3 , Gary Beasley  4 , Renata Shih  5 , Vernat Exil  6 , Juan Alejos  7 , Gonzalo Wallis  8 , Estela Azeka  9 , Deipanjan Nandi  10 , Elizabeth Profita  11 , Joseph Spinner  12 , Defne Magnetta  13 , Hugo Martinez  4 , Matthew Fenton  14 , Jennifer Conway  15 , Simon Urschel  15
Affiliations
Review

Clinical approach to antibody-mediated rejection from the pediatric heart transplant society

Shahnawaz Amdani et al. Pediatr Transplant. 2022 Dec.

Abstract

This document is designed to outline the definition, pathogenesis, diagnostic modalities and therapeutic measures to treat antibody-mediated rejection in children postheart transplant METHODS: Literature review was conducted by a Pediatric Heart Transplant Society (PHTS) working group to identify existing pediatric and adult studies on antibody-mediated rejection (AMR). In addition, the centers participating in PHTS were asked to submit their approach to diagnosis and management of pediatric AMR. This document synthesizes information gathered from both these sources to highlight a practical approach to diagnosing and managing a child with AMR postheart transplant. This document may not represent the practice at all centers in the PHTS and serves as a starting point to understand an approach to this clinical scenario.

Keywords: AMR; heart transplant; pediatric.

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References

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