Selective Decontamination of the Digestive Tract: An Answer at Last?

doi:10.1001/jama.2022.18623

Editorial

. 2022 Dec 20;328(23):2310-2311.

doi: 10.1001/jama.2022.18623.

Selective Decontamination of the Digestive Tract: An Answer at Last?

Marc Bonten¹

Affiliations

PMID: 36378275
DOI: 10.1001/jama.2022.18623

Editorial

Selective Decontamination of the Digestive Tract: An Answer at Last?

Marc Bonten. JAMA. 2022.

. 2022 Dec 20;328(23):2310-2311.

doi: 10.1001/jama.2022.18623.

Author

Marc Bonten¹

Affiliation

¹ Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

PMID: 36378275
DOI: 10.1001/jama.2022.18623

No abstract available

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Comment on

Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.
SuDDICU Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group; Myburgh JA, Seppelt IM, Goodman F, Billot L, Correa M, Davis JS, Gordon AC, Hammond NE, Iredell J, Li Q, Micallef S, Miller J, Mysore J, Taylor C, Young PJ, Cuthbertson BH, Finfer SR. SuDDICU Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group, et al. JAMA. 2022 Nov 15;328(19):1911-1921. doi: 10.1001/jama.2022.17927. JAMA. 2022. PMID: 36286097 Free PMC article. Clinical Trial.
Association Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis.
Hammond NE, Myburgh J, Seppelt I, Garside T, Vlok R, Mahendran S, Adigbli D, Finfer S, Gao Y, Goodman F, Guyatt G, Santos JA, Venkatesh B, Yao L, Di Tanna GL, Delaney A. Hammond NE, et al. JAMA. 2022 Nov 15;328(19):1922-1934. doi: 10.1001/jama.2022.19709. JAMA. 2022. PMID: 36286098 Free PMC article.

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[What is new … in selective decontamination?].
Liebchen U, Briegel J, Scharf C. Liebchen U, et al. Anaesthesiologie. 2023 Apr;72(4):273-274. doi: 10.1007/s00101-023-01262-8. Epub 2023 Feb 16. Anaesthesiologie. 2023. PMID: 36797534 German. No abstract available.
Does selective digestive decontamination (SDD) increase antibiotic resistance? Long-term comparison of two intensive care units (with and without SDD) of the same tertiary hospital.
Rodríguez-Gascón A, Lloréns-Villar Y, Solinís MÁ, Barrasa H, Canut-Blasco A. Rodríguez-Gascón A, et al. Eur J Clin Microbiol Infect Dis. 2024 May;43(5):885-893. doi: 10.1007/s10096-024-04792-0. Epub 2024 Mar 9. Eur J Clin Microbiol Infect Dis. 2024. PMID: 38460030 Free PMC article.
Fecal metabolite profiling identifies critically ill patients with increased 30-day mortality.
de Porto AP, Dylla NP, Stutz M, Lin H, Khalid M, Mullowney MW, Little J, Rose A, Moran D, McMillin M, Burgo V, Smith R, Woodson C, Metcalfe C, Ramaswamy R, Lehmann C, Odenwald M, Bandealy N, Zhao J, Kim M, Adler E, Sundararajan A, Sidebottom A, Kress JP, Wolfe KS, Pamer EG, Patel BK. de Porto AP, et al. Sci Adv. 2025 Jun 6;11(23):eadt1466. doi: 10.1126/sciadv.adt1466. Epub 2025 Jun 4. Sci Adv. 2025. PMID: 40465720 Free PMC article.
Gut Microbiome-Based Therapeutics in Critically Ill Adult Patients-A Narrative Review.
He S, Lin F, Hu X, Pan P. He S, et al. Nutrients. 2023 Nov 9;15(22):4734. doi: 10.3390/nu15224734. Nutrients. 2023. PMID: 38004128 Free PMC article. Review.
Optimizing microbiological surveillance during selective digestive decontamination in the intensive care unit: an in silico simulation study.
Haitsma Mulier JLG, van Dijk FJ, Schweitzer VA, Bonten MJM, Derde LPG, Cremer OL. Haitsma Mulier JLG, et al. Crit Care. 2025 Jun 17;29(1):246. doi: 10.1186/s13054-025-05494-5. Crit Care. 2025. PMID: 40528229 Free PMC article.

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Selective Decontamination of the Digestive Tract: An Answer at Last?

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