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Case Reports
. 2022 Oct 14;4(4):205-208.
doi: 10.36628/ijhf.2022.0019. eCollection 2022 Oct.

Acute Myocarditis After COVID-19 Vaccination

Dae Young Cheon  1 , Sunki Lee  1 , Myung Soo Park  1 , Do Young Kim  1 , Mi-Hyang Jung  1 , Jae Hyuk Choi  1 , Seongwoo Han  1 , Kyu-Hyung Ryu  1
Affiliations
Case Reports

Acute Myocarditis After COVID-19 Vaccination

Dae Young Cheon et al. Int J Heart Fail. .
No abstract available

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Conflict of interest statement

Conflict of Interest: The authors have no financial conflicts of interest.

Figures

Figure 1
Figure 1. Echocardiography and LV global strain on hospital day 2 and 6.
(A, B) Severe hypokinesia of the whole LV apex was observed from initial TTE. (C) LV golbal strain image on same day (HD 2), which was a compatible finding of LV apical hypokinesia in TTE. (D, E) on HD 6, there is no more hypokinesia on TTE. (F) As same as TTE, LV strain was fully recovered. LV = left ventricle; TTE = transthoracic echocardiogram; HD = hospital day.
Figure 2
Figure 2. Cardiac MRI revealed mid- and sub epicardial band-like delayed enhancement in LV apical walls and interventricular septum (white arrow).
MRI = magnetic resonance image; LV = left ventricle.
Figure 3
Figure 3. Endomyocardial biopsy.
(A) H&E stain, A few of inflammatory cell infiltration was found. (B) CD20+ stain which representative marker of B-lymphocyte, was not appear in histology. (C, D) CD3+ & CD68+ stain, suggests lymphocyte and monocyte/macrophage cells, were focal positive in myocardium. H&E = hematoxylin and eosin.
See this image and copyright information in PMC

References

    1. Choi S, Lee S, Seo JW, et al. Myocarditis-induced sudden death after BNT162b2 mRNA COVID-19 vaccination in Korea: case report focusing on histopathological findings. J Korean Med Sci. 2021;36:e286. - PMC - PubMed
    1. Bae DH, Kim M, Lee DI, et al. Simultaneous occurrence of immune-mediated thrombocytopenia and myocarditis after mRNA-1273 COVID-19 vaccination: a case report. J Korean Med Sci. 2022;37:e169. - PMC - PubMed
    1. Kiblboeck D, Klingel K, Genger M, et al. Myocarditis following mRNA COVID-19 vaccination: call for endomyocardial biopsy. ESC Heart Fail. 2022;9:1996–2002. - PMC - PubMed
    1. Grant RA, Morales-Nebreda L, Markov NS, et al. Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia. Nature. 2021;590:635–641. - PMC - PubMed

Publication types