Recent Advancements in In Vitro Fertilisation

Abstract

The field of assisted reproductive technologies has witnessed many new developments over the past 10 years. This review examines new stimulation techniques that might increase the number of fully developed oocytes derived during the in vitro fertilisation (IVF) cycle in addition to strategies for enhancing oocyte quality in older women. Before moving on to several fresh methods for determining endometrial receptivity, we talk about how preimplantation genetic screening (PGS) is currently being utilised. The main goal of this review is to highlight technological fields that might be debatable or are still sufficiently novel to require rigorous controlled trials for recognition. The use of IVF has been on the rise recently, mostly as a result of deferred childbearing, and there is no reason to believe that this trend will alter. Infertility therapies have advanced significantly thanks to the methods and techniques that were established via studies on animals and, more recently, people. Some technical discoveries in reproductive medicine have had a significant impact on innovations and treatment choices in other fields of medicine as well. The objective of this succinct review article is to quickly summarise and explain the advancements made in this intriguing area of medicine over the past 40 years.

Keywords: co-enzyme q10; in vitro fertilization (ivf); infertility; letrozole; pre-implantation genetic screening; reproductive genetics.

Figure 1. Virulent cycle between mitochondria dysfunction and oxidative stress damage

Mitochondria play an integral role in maintaining oocyte quality [6]

Figure 2. In vivo method of CoQ10 supplementation

CoQ10 is directly administered to the patient in the form of oral tablets [6] CoQ10: coenzyme Q10

Figure 3. In vitro method of CoQ10 supplementation

CoQ10 is supplied to the culture media containing oocytes [6] CoQ10: coenzyme Q10