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. 2022 Nov 11;24(Suppl H):H3-H7.
doi: 10.1093/eurheartjsupp/suac057. eCollection 2022 Nov.

Cardiovascular prevention: sometimes dreams can come true

Roberto Ferrari  1 , Paolo Cimaglia  2 , Claudio Rapezzi  1   2 , Luigi Tavazzi  2 , Gabriele Guardigli  1
Affiliations

Cardiovascular prevention: sometimes dreams can come true

Roberto Ferrari et al. Eur Heart J Suppl. .

Abstract

Cardiovascular disease (CVD) is a chronic condition driven by the complex interaction of different risk factors including genetics, lifestyle, environment, etc. which, differently from other pathologies, can be prevented. Treatment of CVD has been inconceivably successful but now it seems that it has reached a plateau suggesting that prevention is the way forward. However, the COVID-19 pandemic has spotted all the limits of the actual health system regarding territorial and, particularly, of preventive medicine. To this end, recently, the SCORE2 risk prediction algorithms, a contemporary model to estimate 10-years risk of CVD in Europe and the new guidelines on prevention have been released. The present review article describes a dream: how prevention of CVD should be addressed in the future. New concepts and paradigms like early genetically personalized and imaging driven risk factors, cardiac risk cartography, measurements of the exposome, estimation of costs of a delayed outcome vs. healthy lifespan, are all addressed. We highlight the importance of technologies and the concept of being engaged in a 'healthy' and not just 'sick' system as it is today. The concept of 'clearing house' with a 'healthcare team' instead of a 'heart team' is described. Finally, we articulate the four points necessary for the dream to come true.

Keywords: CVD; Health system; Prevention; Risk scores.

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Conflict of interest statement

Conflict of interest: R.F. reports having received research grants and personal fees from Novartis and Servier personal fees from Merck Serono, Boehringer Ingelheim, Sunpharma, Lupin, Doc Generici, Pfizer, Spa Prodotti Antibiotici outside the submitted work. He is a director of Art Research and Science S.r.l (A.R.S.1). P.C. has no conflict of interest to disclose. C.R. reports grants and personal fees from Pfizer, personal fees from Sanofi, personal fees from Novartis, personal fees from Alnylam Pharmaceuticals, outside the submitted work. L.T. reports personal fees from SERVIER, personal fees from CVIE THERAPEUTICS outside the submitted work. G.G. has no conflict of interest to disclose.

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