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Review
. 2022 Nov 16;14(671):eabo6646.
doi: 10.1126/scitranslmed.abo6646. Epub 2022 Nov 16.

The RTS,S malaria vaccine: Current impact and foundation for the future

James G Beeson  1   2   3 , Liriye Kurtovic  1   3 , Clarissa Valim  4 , Kwaku Poku Asante  5 , Michelle J Boyle  6   7   8 , Don Mathanga  9 , Carlota Dobano  10   11 , Gemma Moncunill  10   11
Affiliations
Review

The RTS,S malaria vaccine: Current impact and foundation for the future

James G Beeson et al. Sci Transl Med. .

Abstract

The RTS,S vaccine has recently been recommended for implementation as a childhood vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of vaccine protection and longevity, implementation considerations, and future research needed to increase the vaccine's health impact, including vaccine modifications for higher efficacy and longevity of protection.

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