Bone marrow chimerism breaks the barrier to pancreatic islet transplantation
- PMID: 36384104
- DOI: 10.1016/j.celrep.2022.111692
Bone marrow chimerism breaks the barrier to pancreatic islet transplantation
Abstract
In their recent Cell Reports paper, Chang and colleagues report on a successful strategy to achieve durable mixed hematopoietic chimerism that promotes the engraftment and long-term function of pancreatic islet allotransplants in fully immunocompetent mice without immunosuppression.
Published by Elsevier Inc.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning.Cell Rep. 2022 Nov 8;41(6):111615. doi: 10.1016/j.celrep.2022.111615. Cell Rep. 2022. PMID: 36351397 Free PMC article.
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