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Comment
. 2022 Nov;611(7937):670-671.
doi: 10.1038/d41586-022-03371-7.

Alzheimer's risk variant APOE4 linked to myelin-assembly malfunction

Karl Carlström, Gonçalo Castelo-Branco
Comment

Alzheimer's risk variant APOE4 linked to myelin-assembly malfunction

Karl Carlström et al. Nature. 2022 Nov.
No abstract available

Keywords: Alzheimer's disease; Brain; Neuroscience.

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Comment on

  • APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
    Blanchard JW, Akay LA, Davila-Velderrain J, von Maydell D, Mathys H, Davidson SM, Effenberger A, Chen CY, Maner-Smith K, Hajjar I, Ortlund EA, Bula M, Agbas E, Ng A, Jiang X, Kahn M, Blanco-Duque C, Lavoie N, Liu L, Reyes R, Lin YT, Ko T, R'Bibo L, Ralvenius WT, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Nature. 2022 Nov;611(7937):769-779. doi: 10.1038/s41586-022-05439-w. Epub 2022 Nov 16. Nature. 2022. PMID: 36385529 Free PMC article.

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