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Comment
. 2023 Jan;20(1):5.
doi: 10.1038/s41569-022-00813-7.

siRNA therapy markedly reduces Lp(a) levels

Irene Fernández-Ruiz  1
Affiliations
Comment

siRNA therapy markedly reduces Lp(a) levels

Irene Fernández-Ruiz. Nat Rev Cardiol. 2023 Jan.
No abstract available

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Comment on

  • Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease.
    O'Donoghue ML, Rosenson RS, Gencer B, López JAG, Lepor NE, Baum SJ, Stout E, Gaudet D, Knusel B, Kuder JF, Ran X, Murphy SA, Wang H, Wu Y, Kassahun H, Sabatine MS; OCEAN(a)-DOSE Trial Investigators. O'Donoghue ML, et al. N Engl J Med. 2022 Nov 17;387(20):1855-1864. doi: 10.1056/NEJMoa2211023. Epub 2022 Nov 6. N Engl J Med. 2022. PMID: 36342163 Clinical Trial.

References

Original article
    1. O’Donoghue, M. L. et al. Small interfering RNA to reduce lipoprotein(a) in cardiovascular disease. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2211023 (2022) - DOI

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