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Case Reports
. 2022 Nov 7:2022:8705143.
doi: 10.1155/2022/8705143. eCollection 2022.

Adenocarcinoma Metastasis from Colon to the Thyroid

Parviz Mardani  1 , Nazanin Ayareh  2 , Hooman Kamran  1   2 , Reza Shahriarirad  1   2 , Masoud Vafabin  1 , Neda Soleimani  3   4
Affiliations
Case Reports

Adenocarcinoma Metastasis from Colon to the Thyroid

Parviz Mardani et al. Case Rep Surg. .

Abstract

Background: Colorectal cancer metastasis to the thyroid is extremely rare and happens in the late course of the disease. Case Description. Here is the report of a 55-year-old female patient who came to us with the chief complaint of cough, diagnosed with colon metastasize to the lung. Surgical resection of the mass was performed. However, a thyroid mass was found incidentally in her postoperative follow-up. Fine needle aspiration of thyroid mass showed papillary thyroid carcinoma. But, after thyroidectomy, the origin of the mass was reported to be adenocarcinoma metastasis from colon cancer.

Conclusion: Although thyroid metastasis from colorectal cancer rarely occurs, it should be considered in a patient with a solitary thyroid nodule and a past medical history of colon cancer. Surgical treatment is the preferred choice of treatment in these cases.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Computed tomography scan showing a mass in the upper part of the left lung: (a) coronal view and (b) sagittal view.
Figure 2
Figure 2
Chest X-ray of our patient on the day that she presented with dyspnea and chest pain.
Figure 3
Figure 3
Cut section of the thyroid shows an ill-defined creamy firm mass in the right lobe.
Figure 4
Figure 4
Microscopic sections show metastatic glands of colon adenocarcinoma, infiltrating between thyroid follicles: (a) H&E ×40 and (b) (H&E ×200). The metastatic gland shows immunoreactivity for CK7 (c) and CK20 (d).
Figure 5
Figure 5
Cytology smear shows moderate number of isolated and clusters of highly atypical cells.
See this image and copyright information in PMC

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